Director, Quantitative Clinical Pharmacology PK/PD Strategy

Sarepta Therapeutics; New Jersey; Hybrid; USD 186,000 - 232,000; Full time

Benefits offered by this job

Physical and Emotional Wellness

Financial Wellness

Support for Caregivers

Job summary

Sarepta Therapeutics seeks a Director of Quantitative & Clinical Pharmacology to lead pharmacology and pharmacometrics across clinical development, shaping dose selection and predictive modeling. The role emphasizes population PK/PD analyses, translational science, and regulatory interactions, with leadership across global teams.

The position is hybrid, on-site at Sarepta facilities in the United States, with opportunities to influence program strategy and scientific communication.

Qualifications

• PhD in Pharmaceutical Sciences, mathematics/engineering or related field with 7 years of experience in clinical pharmacology or pharmacometrics.
• Strong PK/PD modeling knowledge and regulatory interaction experience.
• Excellent communication, multitasking and collaboration skills.
• Experience with NONMEM and R highly preferred.
• siRNA and/or CNS experience is preferred.

Responsibilities

• Lead clinical pharmacology and pharmacometrics deliverables across drug development from early to registration.
• Drive model-based analyses including population PK, PK/PD modeling, meta-analysis, and disease modeling.
• Provide regulatory strategy input and HA engagement support.
• Mentor teams and publish findings at scientific forums.

Skills

Clinical pharmacology

PK/PD modeling

Regulatory interactions

Communication

Leadership

Education

PhD in Pharmaceutical Sciences

Tools

NONMEM

R

Job description

Sarepta Therapeutics seeks a Director of Quantitative & Clinical Pharmacology to lead pharmacology and pharmacometrics across clinical development, shaping dose selection and predictive modeling. The role emphasizes population PK/PD analyses, translational science, and regulatory interactions, with leadership across global teams.

The position is hybrid, on-site at Sarepta facilities in the United States, with opportunities to influence program strategy and scientific communication.