Director, Protein Biochemistry & Single-Molecule Science

Pacific Biosciences; United States; On-site; USD 196,000 - 294,000; Full time

Job summary

Pacific Biosciences seeks a Director of Protein Biochemistry to lead protein engineering and single-molecule biochemistry efforts for its long-read sequencing platforms. This role directs a five-person, multidisciplinary team spanning biochemistry, engineering, microscopy, biophysics, enzymology, and computational analysis.

The candidate will establish scientific priorities, guide characterizations, and collaborate with cross-functional partners to translate research into platform improvements.

Qualifications

• PhD in biochemistry, biophysics, molecular biology, bioengineering, or related field.
• 15+ years of industry experience.
• 10+ years of management experience leading scientific teams.
• Strong knowledge of protein and nucleic acid chemistry, structural biology, and sequencing technologies.

Responsibilities

• Direct protein engineering and single-molecule biochemistry research to develop and optimize proteins and biochemical systems for PacBio's sequencing platforms.
• Lead, mentor, and develop a five-person multidisciplinary team across experimental, engineering, and computational disciplines.
• Establish scientific priorities, research plans, and milestones aligned with sequencing platform development goals.
• Guide protein biochemical characterization, single-molecule biophysical measurements, and enzymology studies to inform engineering strategies.
• Integrate microscopy, biochemical measurements, and computational analyses to guide experimental design and decisions.
• Collaborate with cross-functional partners to translate research findings into platform performance improvements.

Skills

Protein engineering

Biochemistry

Single-molecule biochemistry

Biophysics

Education

PhD in biochemistry, biophysics, molecular biology, bioengineering, or a closely related discipline

Tools

Single-molecule microscopy

Enzymology

Job description

Pacific Biosciences seeks a Director of Protein Biochemistry to lead protein engineering and single-molecule biochemistry efforts for its long-read sequencing platforms. This role directs a five-person, multidisciplinary team spanning biochemistry, engineering, microscopy, biophysics, enzymology, and computational analysis.

The candidate will establish scientific priorities, guide characterizations, and collaborate with cross-functional partners to translate research into platform improvements.