Director, Oncology Medicinal Chemistry

Bristol-Myers Squibb Co; San Diego (CA); On-site; USD 232,000 - 281,000; Full time

Benefits offered by this job

Flexible Time Off (FTO)

11 paid holidays

160 hours paid vacation for new hires

Annual Global Shutdown

Comprehensive benefits

Job summary

Bristol Myers Squibb in San Diego, CA is seeking an experienced medicinal chemist to lead and contribute to the drug discovery portfolio within the Protein Homeostasis Thematic Research Center. The role involves guiding a team to design and advance oncology agents using modern drug design principles and interdisciplinary collaboration.

You will participate in portfolio strategy, resource allocation, and senior leadership discussions while mentoring a high-performing chemistry group to deliver

Qualifications

• Ph.D. in synthetic organic chemistry with 8+ years pharmaceutical medicinal chemistry industrial experience.
• M.S. in synthetic organic chemistry with 12+ years pharmaceutical medicinal chemistry industrial experience.
• B.S. in synthetic organic chemistry with 15+ years pharmaceutical medicinal chemistry industrial experience.
• 6+ years of program leadership experience in all drug discovery phases from program initiation to development candidate identification.
• Excellent communication skills, including the presentation of strategy, key data, issues and accomplishments to other members of the organization.
• Experience in the field of protein degradation or induced proximity a plus.

Responsibilities

• Lead end-to-end medicinal chemistry programs from discovery through IND, driving strategy, execution, and delivery of high-impact oncology assets
• Design and advance novel compounds using state-of-the-art drug design approaches, integrating structural biology, ADME, and computational insights
• Partner across multidisciplinary teams to accelerate decision-making, shape portfolio strategy, and deliver transformative therapeutics
• Build, mentor, and lead high-performing scientific teams, fostering a culture of innovation, accountability, and scientific excellence within and outside direct reporting lines
• Clearly articulate program strategy, data, opportunities, and risks to senior leadership and key stakeholders
• As a member of the San Diego Chemistry Leadership team, drive the scientific, strategic, and operational direction of the San Diego medicinal chemistry organization, including portfolio prioritization, resource allocation, talent development, and representation in senior leadership decision-making

Skills

leadership

strategic thinking

communication

drug discovery

Education

Ph.D. in synthetic organic chemistry

M.S. in synthetic organic chemistry

B.S. in synthetic organic chemistry

Job description

Bristol Myers Squibb in San Diego, CA is seeking an experienced medicinal chemist to lead and contribute to the drug discovery portfolio within the Protein Homeostasis Thematic Research Center. The role involves guiding a team to design and advance oncology agents using modern drug design principles and interdisciplinary collaboration.

You will participate in portfolio strategy, resource allocation, and senior leadership discussions while mentoring a high-performing chemistry group to deliver