Senior Director, Medicinal Chemistry - Oncology

VetJobs; San Diego (CA); On-site; USD 232,000 - 281,000; Full time

Job summary

Bristol Myers Squibb in San Diego seeks an experienced medicinal chemist to lead the drug discovery portfolio within the Protein Homeostasis Thematic Research Center. The role focuses on rational design of new oncology agents and collaboration with global discovery teams to advance assets toward IND.

The candidate will guide a team of scientists, applying modern design principles, and will participate in senior leadership decisions shaping portfolio strategy and resource allocation in a dynamic

Qualifications

• Ph.D. in synthetic organic chemistry with 8+ years pharmaceutical medicinal chemistry industrial experience
• M.S. in synthetic organic chemistry with 12+ years pharmaceutical medicinal chemistry industrial experience
• B.S. in synthetic organic chemistry with 15+ years pharmaceutical medicinal chemistry industrial experience
• 6+ years of program leadership experience in all drug discovery phases from program initiation to development candidate identification
• Excellent communication skills, including the presentation of strategy, key data, issues and accomplishments
• Experience in the field of protein degradation or induced proximity is a plus

Responsibilities

• Lead end-to-end medicinal chemistry programs from discovery through IND, driving strategy, execution, and delivery of high-impact oncology assets
• Design and advance novel compounds using state-of-the-art drug design approaches, integrating structural biology, ADME, and computational insights
• Partner across multidisciplinary teams to accelerate decision-making, shape portfolio strategy, and deliver transformative therapeutics
• Build, mentor, and lead high-performing scientific teams, fostering a culture of innovation, accountability, and scientific excellence within and outside direct reporting lines
• Clearly articulate program strategy, data, opportunities, and risks to senior leadership and key stakeholders
• As a member of the San Diego Chemistry Leadership team, drive the scientific, strategic, and operational direction of the San Diego medicinal chemistry organization, including portfolio prioritization, resource allocation, talent development, and representation in senior leadership decision-making

Job description

Bristol Myers Squibb in San Diego seeks an experienced medicinal chemist to lead the drug discovery portfolio within the Protein Homeostasis Thematic Research Center. The role focuses on rational design of new oncology agents and collaboration with global discovery teams to advance assets toward IND.

The candidate will guide a team of scientists, applying modern design principles, and will participate in senior leadership decisions shaping portfolio strategy and resource allocation in a dynamic