Director, Oligonucleotide Process Chemistry & CMC

Initial Therapeutics, Inc.; Indianapolis (IN); On-site; USD 148,500 - 257,400; Full time

Benefits offered by this job

Company-sponsored 401(k)

Comprehensive medical benefits

Flexible spending accounts

Job summary

Initial Therapeutics, Inc. is seeking a skilled scientist for their Synthetic Molecule Design and Development team in Indianapolis, IN. This role requires extensive expertise in oligonucleotide CMC, focusing on the development and optimization of synthetic drug processes. Qualified candidates must hold a PhD or MS and possess several years of industry experience. Responsibilities include leading CMC activities for clinical trials, developing impurity control strategies, and collaborating with internal and external partners. Competitive compensation package offered including health benefits.

Qualifications

• 5+ years of relevant industry experience in synthesis, oligonucleotides, and CMC.
• Experience in pharmaceutical sector active ingredient development.
• Tech transfer experience into manufacturing operations.

Responsibilities

• Lead CMC activities to support clinical trials and regulatory submissions.
• Develop and apply impurity control strategies.
• Provide technical leadership for process scale-up.

Skills

Oligonucleotide CMC expertise

Synthesis

Solid-phase synthesis

Process development

Regulatory interactions

Education

PhD in a relevant scientific discipline

MS in a relevant scientific discipline

Job description

Initial Therapeutics, Inc. is seeking a skilled scientist for their Synthetic Molecule Design and Development team in Indianapolis, IN. This role requires extensive expertise in oligonucleotide CMC, focusing on the development and optimization of synthetic drug processes. Qualified candidates must hold a PhD or MS and possess several years of industry experience. Responsibilities include leading CMC activities for clinical trials, developing impurity control strategies, and collaborating with internal and external partners. Competitive compensation package offered including health benefits.