Director, Data Solutions — Real‑World Evidence & Insights

Tempus AI, Inc.; Chicago (IL); On-site; USD 180,000 - 230,000; Full time

Job summary

Tempus AI, Inc. seeks a Director, Data Solutions – RWE & Insights to lead scientific strategy for pharma partnerships, guiding analyses of real-world evidence across multimodal data.

You will design studies, mentor scientists, and collaborate with product and clinical teams, travel ~20%, and drive revenue while maintaining scientific rigor. This role anchors Tempus' commitment to precision medicine and requires a PhD/MD and a track record in oncology and RWE.

Qualifications

• PhD, MD, or equivalent advanced degree combining quantitative or computational training with biological or medical knowledge.
• Deep expertise in oncology and in Real World Evidence, Translational Research / Computational Biology, or Drug Discovery methodologies.
• Hands-on proficiency in R, including statistical and visualization tooling.
• Experience with clinical trial design, real-world evidence study design, and integrative methods for multimodal clinical and omics data.
• A track record of scientific output, such as publications, regulatory or HTA submissions, or partner-facing study results.
• Proven ability to build deep, trusted relationships with pharmaceutical scientists and executives based on scientific credibility.
• A leader who fosters a collaborative and inclusive environment that promotes creativity, innovation, and scientific excellence.
• Proactive mindset that bridges ideas to implementable solutions; comfortable in agile environments with quick iterations.

Responsibilities

• Serve as the senior scientific advisor to biopharma partners, translating their pipeline, biomarker, and clinical development questions into feasible, well-designed analyses using Tempus clinical, molecular, and imaging data.
• Personally design and execute proof-of-value analyses and cohort feasibility assessments for high-priority or complex opportunities.
• Define the scientific approach for real-world evidence and translational projects, including study design, endpoint selection, cohort definition, and statistical and computational methods.
• Review and sign off on the scientific content of scopes, SOWs, and deliverables produced by the team, ensuring methodological rigor and accurate representation of the data.
• Present findings to partner R&D and clinical teams, and contribute to publications, posters, and conference presentations where appropriate.
• Stay current on oncology drug development, real-world data methodology, regulatory use of RWE, and AI and multimodal modeling.
• Partner with Tempus product, data science, and abstraction teams to identify data gaps surfaced by partner needs and shape the roadmap for new data products.
• Mentor and develop more junior Data Solutions scientists, growing their domain knowledge as well as their client-facing skills.
• Assign and flex team members across pharma, biotech, and innovation-economy accounts based on expertise and opportunity value.
• Build standardized, scalable scientific workflows (feasibility templates, analysis frameworks, data POVs) so the team can rapidly support more partners without lowering quality.
• Act as the first point of escalation for complex or non-standard scientific requests, and involve senior leadership early on enterprise-level opportunities.
• Travel approximately 20% of working time, domestically and internationally.
• Other duties as assigned

Skills

R programming

Biostatistics

Clinical trial design

Real World Evidence

Scientific leadership

Education

PhD, MD or equivalent advanced degree

Tools

R

Job description

Tempus AI, Inc. seeks a Director, Data Solutions – RWE & Insights to lead scientific strategy for pharma partnerships, guiding analyses of real-world evidence across multimodal data.

You will design studies, mentor scientists, and collaborate with product and clinical teams, travel ~20%, and drive revenue while maintaining scientific rigor. This role anchors Tempus' commitment to precision medicine and requires a PhD/MD and a track record in oncology and RWE.