Director, CNS Therapeutics & Translational Neurobiology

Broad Institute of MIT and Harvard; Cambridge (MA); On-site; USD 250,000 - 350,000; Full time

Benefits offered by this job

Medical insurance

Dental insurance

Vision insurance

401(k)

Job summary

The Broad Institute, through its Stanley Center for Psychiatric Research, seeks a Director of Therapeutics Translational Neurobiology to shape scientific strategy, identify novel targets, and lead execution across preclinical programs in CNS disorders.

Reporting to Morgan Sheng, the role will build and manage a small team, collaborate with internal scientists, and advance targets from validation to preclinical proof-of-concept, while representing the center externally.

Qualifications

• Ph.D. or M.D./Ph.D. in Neuroscience, Pharmacology, Molecular/Cell Biology, Chemistry, or related life sciences field required
• 10+ years of drug discovery in industry with leadership of multi-project programs; CNS/psychiatric disease experience required
• 7+ years managing a team of scientists; hiring, mentoring, and performance development
• Direct experience managing a multi-project portfolio with prioritization and resourcing decisions
• Exposure to external partnership development, licensing discussions, or business development in biotech/pharma or academic drug discovery
• Comfort operating in a matrixed organization balancing scientific direction with program ownership
• Excellent written and verbal communication skills with senior leadership and external partners

Responsibilities

• Define and drive scientific strategy across a portfolio of several therapeutics projects, translating human genetic and biological insights into drug discovery plans
• Collaborate on strategic planning and resource allocation across the broader therapeutics program
• Own portfolio-level budget planning and managerial oversight across several preclinical therapeutics projects
• Oversee and mentor project leads, while building a team to prosecute new targets
• Foster a culture of scientific rigor, collaboration, and professional growth
• Make go/no-go and prioritization calls as data mature, balancing science, feasibility, and fit with the Center’s mission
• Build and maintain relationships with biotech and pharma companies for external alliances
• Represent the Stanley Center’s therapeutics work externally in partnerships and conferences

Skills

Leadership

Portfolio management

Budget planning

Strategic planning

Drug discovery

Scientific communication

Cross-functional collaboration

Education

Ph.D./M.D.- Ph.D.

Job description

The Broad Institute, through its Stanley Center for Psychiatric Research, seeks a Director of Therapeutics Translational Neurobiology to shape scientific strategy, identify novel targets, and lead execution across preclinical programs in CNS disorders.

Reporting to Morgan Sheng, the role will build and manage a small team, collaborate with internal scientists, and advance targets from validation to preclinical proof-of-concept, while representing the center externally.