Director, Clinical Research

Hello Heart; United States; Remote; USD 180,000 - 197,000; Full time

Job summary

Hello Heart is seeking a Director of Clinical Research to lead the clinical and economic evidence strategy for AI-based heart health products, partnering across Commercial, Medical Affairs, Data Science, and Product to publish peer-reviewed work and client-facing evidence.

You will apply advanced statistics and work with datasets (clinical, claims, EHR) to drive publication pipelines, regulatory-ready analyses, and collaborations with research institutes, translating findings for technical and

Qualifications

• Graduate degree in a clinical field, epidemiology, biostatistics, public health, or related field, with 10+ years of clinical research experience.
• Experience in commercial research settings balancing rigor with business needs.
• Experience leading or mentoring a team of researchers and supporting independent publication.
• Strong statistical programming experience with R, Python, SQL, MS Excel, or similar tools.
• Strong AI fluency to design AI-enabled workflows while ensuring accuracy, privacy, and human review.

Responsibilities

• Collaborate with leadership to prioritize clinical and economic research.
• Provide peer review and mentorship for researchers on the team.
• Develop analytical plans for publication and evidence-generation priorities.
• Build partnerships with leading research institutes.
• Shape the study pipeline for FDA-regulated capabilities.

Skills

Statistical programming (R, Python,SQL

AI fluency

Data analysis & visualization

Clinical/claims/EHR datasets

Education

Graduate degree in epidemiology/biostatistics/public health or clinical field

Tools

R

Python

SQL

Excel

Job description

Hello Heart is on a mission to make heart attacks a thing of the past.

We’re an AI company focused exclusively on heart health, building a platform that predicts and prevents cardiac events before they happen—identifying risk up to 10 days in advance versus 10 years in traditional clinical models.

This is already working at scale. Hello Heart has been shown to reduce inpatient hospital days by 47% and deliver ~$1,800 in annual savings per member.Hello Heart is the cardiac prevention partner to over 80% of large U.S. health plans and serves hundreds of public and private employers.
We’re defining how the #1 cause of death—heart disease—is managed in the AI era. Join us.

About the Role

Hello Heart is seeking a Director, Clinical Research to lead the clinical and economic evidence strategy to showcase how Hello Heart products help members understand and improve their heart health through AI, hardware, and behavioral science.

Reporting into our VP, Commercial Actuary, you will set our research and publications strategy; partnering with Commercial & Product Leadership, Medical Affairs, Data Science, Product, Sales, and Marketing to drive peer reviewed publications, white papers, conference abstracts, and client facing evidence that support our commercial goals. You will apply your expertise in statistics, claims analysis, and clinical research to shape our study pipeline, build partnerships with leading research institutes and consultants, and represent Hello Heart’s evidence to technical and executive audiences.

This is a strong fit for someone who enjoys rigorous research, clear communication, cross-functional collaboration, and turning complex data into evidence that supports better heart health outcomes.

What you’ll do

• Collaborate with leadership and cross-functional partners to prioritize clinical and economic research priorities.
• Provide peer review and mentorship to other researchers on the team, developing their analytical and publication skills over time.
• Generate research questions and develop analytical plans for key publication and evidence-generation priorities.
• Develop partnerships and work alongside leading research institutes.
• Build Hello Heart's research and evidence strategy to support future FDA-regulated capabilities, accounting for regulatory requirements and timelines.
• Identify, organize, query, and analyze diverse datasets, including clinical, claims, electronic health record (EHR), and engagement data.
• Apply advanced statistical methods, including multilevel modeling, causal inference methods, propensity score matching, mixed-effects modeling, longitudinal analyses, and sensitivity testing.
• Collaborate with co-authors to incorporate feedback and finalize analyses, manuscripts, white papers, and abstracts.
• Respond to anonymous peer reviews, including repeat analyses and manuscript revisions, to support timely resubmission.
• Identify relevant conferences for abstract submission and present ongoing research when appropriate.
• Stay current on scientific research related to cardiovascular health, digital health, behavioral science, chronic disease, health economics, and public health.
• Contribute to data summaries, research protocols, institutional review board (IRB) materials, and other research documentation.
• Translate complex analytical findings into clear, accurate, and actionable insights for clinical, technical, commercial, and executive audiences.

What you’ll bring

• Graduate degree in a clinical field, epidemiology, biostatistics, public health, or a related field, such as Master of Science (MS), Master of Public Health (MPH), Doctor of Philosophy (PhD), or Doctor of Pharmacy (PharmD), with 10+ years of clinical research experience.
• Demonstrated experience working in a commercial research setting, comfortable balancing scientific rigor with business needs.
• Experience leading or mentoring a team of researchers, including peer-reviewing others' work and supporting less experienced researchers as they develop toward independent publication.
• Strong statistical programming experience with R, Python, SQL, MS Excel, or other relevant analytical tools.
• Strong AI fluency, with the ability to design AI-enabled workflows, such as building or customizing agents others can use while maintaining accuracy, privacy, and human review.
• Strong data skills, including data cleaning, data management, statistical analysis, and data visualization.
• Experience planning and implementing complex statistical analyses while managing deadlines across multiple research priorities.
• Experience working with clinical, claims, electronic health record (EHR), engagement, or other healthcare datasets.
• Experience testing medical claims, pharmacy claims, and enrollment data for errors, including actuarial summaries and cuts by cohort.
• Highly organized, detail-oriented, and able to manage multiple projects at once.
• Open and responsive to feedback on manuscripts, analyses, and other written work.
• Excellent written and verbal communication skills, with the ability to explain findings to technical and non-technical audiences.

The US base salary range for this full-time position is $180,000.00 to $197,000.00. Salary ranges are determined by role and level. Compensation is determined by additional factors, including job-related skills, experience, and relevant education or training. Please note that the compensation details listed in US role postings reflect the annual salary only, and do not include equity or benefits.

Hello Heart has a positive, diverse, and supportive culture - we look for people who are collaborative, creative, and courageous. Oh, and if you want to see some recent evidence of the fun things we do at Hello Heart, check out our Instagram page .

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey.Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiringprocess or thereafter. Any information that you do provide will be recorded and maintained in aconfidential file.

As set forth in Hello Heart’s Equal Employment Opportunity policy,we do not discriminate on the basis of any protected group status under any applicable law.

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection.As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measurethe effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categoriesis as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval, or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.