Director, Clinical Pharmacology & PK/PD Strategy

Bristol-Myers Squibb Co; Princeton (NJ); Hybrid; USD 202,000 - 245,000; Full time

Job summary

Bristol Myers Squibb Co in Princeton, NJ is seeking a Director, Clinical Pharmacology to lead CP&P strategies across development programs, reporting to Senior Director. You will apply PK/PD and model-informed drug development to support decision-making, shape integrated development plans, and guide cross-functional teams.

The role emphasizes mentorship, strong communication, and stakeholder management, with responsibilities spanning study design input, CP&P planning, data analysis, regulatory

Qualifications

• MS, PhD or PharmD in relevant field or a PharmD with clinical pharmacology research fellowship.
• Approximately 7+ years’ experience with demonstrated progression in Clinical Pharmacology and Pharmacometrics, including expertise in the general drug development process and in small molecule and/or biologic drug property characterization.
• In-depth knowledge of current practices and issues in Clinical Pharmacology and Pharmacometrics.
• Strong written and oral communication skills necessary to report on and deliver scientific presentations.
• Demonstrate the ability to work in a dynamic team-oriented environment.
• Manage and provide mentorship and guidance to staff and CP&P function.
• Independently serve as the CP&P lead for one or more assets in the BMS drug development program.
• Demonstrated stakeholder management with strong influence/leadership.
• Programming experience is highly desired (e.g., NONMEM, R, and WinNonlin. SAS, Splus, etc.)
• Quantitative data analysis, POP PK/PD, and data visualization skills are highly desired.

Responsibilities

• Supervise and/or mentor other CP&P leads as appropriate.
• Independently contribute to compound development across various development phases.
• Represent Clinical Pharmacology at asset teams at governance based on proficiency.
• Provide input to Phase 2/3 clinical study design and registrational strategy.
• Accountable for Clinical Pharmacology and Pharmacometrics Plan.
• Lead design of Clinical Pharmacology studies and manages data analysis, interpretation, and reporting.
• High proficiency in PK, PK/PD, and model informed drug development (MIDD) principles and analyses.
• Collaborate on cross-functional drug development teams, regulatory submissions, and departmental initiatives; serves as Clinical Pharmacology subject matter expert.
• Participate in interactions with health authorities; serve as Clinical Pharmacology subject matter expert.
• Lead and participate in departmental initiatives and represent CP&P on cross-functional initiatives / workstreams / taskforces.
• Work with Business Development teams and provide critical expertise to assess external acquisitions.

Skills

PK/PD modeling

MIDD

Leadership

Communication

Data analysis

Cross-functional collaboration

Stakeholder management

Education

MS/PhD or PharmD in relevant field

PharmD with clinical pharmacology fellowship

Tools

NONMEM

R

WinNonlin

SAS

S-Plus

Job description

Bristol Myers Squibb Co in Princeton, NJ is seeking a Director, Clinical Pharmacology to lead CP&P strategies across development programs, reporting to Senior Director. You will apply PK/PD and model-informed drug development to support decision-making, shape integrated development plans, and guide cross-functional teams.

The role emphasizes mentorship, strong communication, and stakeholder management, with responsibilities spanning study design input, CP&P planning, data analysis, regulatory