Director, AI-Driven Drug Design & Molecular Innovation

6084-Janssen Research & Development, LLC Legal Entity; San Diego (CA); Sur place; USD 164 000 - 283 000; Plein temps

Avantages offerts par ce poste

Performance bonus

Comprehensive benefits

Résumé du poste

Johnson & Johnson Innovative Medicine seeks a Director, Computer‑Directed Drug Design and AI‑Native Molecular Design to lead the In Silico Drug Discovery team in San Diego, CA. You will co‑own design strategy, guide AI‑driven molecular design, and align computational decisions with therapeutic program goals.

You will build a high‑performing team, integrate with cross‑functional partners, and scale repeatable learning systems that improve compound quality and portfolio decisions across modalities.

Qualifications

• PhD in computational chemistry, theoretical chemistry, chemical physics, biophysics, cheminformatics, medicinal chemistry, or a related scientific discipline.
• A minimum of 8 years of relevant small-molecule drug-discovery experience, including progressive scientific and people leadership.
• Demonstrated impact across multiple discovery programs from hit identification through lead optimization.
• Deep applied expertise in computational chemistry, cheminformatics, molecular design, and multiparameter optimization.
• Strong medicinal chemistry and molecular architecture judgment with SAR interpretation & portfolio value balance.
• Experience applying and driving adoption of production-grade computational or AI-enabled capabilities in discovery workflows.

Responsabilités

• Co-own program strategy, molecular design priorities, and critical discovery decisions with leaders from multiple disciplines.
• Translate target product profiles and hypotheses into integrated computational and experimental strategies.
• Lead the CD3 team as computational molecular architects ensuring design decisions align with portfolio value.
• Orchestrate design–make–test–learn cycles and reusable platforms with ISD partners.
• Evaluate AI-generated proposals with scientific controls and risk assessment.

Connaissances

Advanced Analytics

Data Analysis

Data Visualization

Leadership

Program Management

Strategic Thinking

Critical Thinking

Data Science

Developing Others

Digital Fluency

Formation

PhD in computational chemistry or related

Description du poste

Johnson & Johnson Innovative Medicine seeks a Director, Computer‑Directed Drug Design and AI‑Native Molecular Design to lead the In Silico Drug Discovery team in San Diego, CA. You will co‑own design strategy, guide AI‑driven molecular design, and align computational decisions with therapeutic program goals.

You will build a high‑performing team, integrate with cross‑functional partners, and scale repeatable learning systems that improve compound quality and portfolio decisions across modalities.