Contract Bioanalytical Scientist (LC-MS/MS) – PK & ADME

Advanced Clinical; Alameda (CA); On-site; USD 85,000 - 120,000; Full time

Benefits offered by this job

Health coverage

Life insurance

Disability insurance

401k benefits

Job summary

Advanced Group seeks a Scientist, Bioanalytical Sciences to support drug discovery and DMPK research with LC-MS/MS bioanalysis of small molecules and PK analysis. The role involves bioanalytical data generation, PK reporting, formulation testing, and ADME-related activities to advance programs.

Ideal candidates will have hands-on LC-MS/MS experience, solid PK knowledge, and experience with biological matrices in a research setting.

Qualifications

• Bachelor's degree in Chemistry or related field with 2+ years' LC-MS/MS bioanalysis
• Experience supporting PK data analysis
• Knowledge of bioanalytical sample preparation and workflows
• Strong data analysis, documentation, and teamwork

Responsibilities

• Perform LC-MS/MS bioanalysis of small molecules in biological matrices (plasma, blood, serum, tissue)
• Conduct bioanalytical testing to support PK, TK, PD, efficacy and drug discovery studies
• Prepare/ process biological samples using established extraction methods
• Operate, maintain, and troubleshoot LC-MS/MS instrumentation and lab equipment
• Perform PK data analysis and contribute to PK reports
• Support DMPK activities through data generation, analysis, reporting, and database management
• Assist with formulation development, testing, and in vitro stability assessments
• Support ADME studies (metabolic stability, hepatocyte, microsomal, plasma stability, protein binding)
• Coordinate with external research partners and contribute to study execution and data review
• Maintain accurate laboratory documentation and communicate findings to project teams

Skills

LC-MS/MS

PK data analysis

Bioanalytical skills

Excel

Communication

Education

Bachelor's in Chemistry

Master's degree in related field

Tools

Phoenix WinNonlin

Mass spectrometry instruments

Job description

Advanced Group seeks a Scientist, Bioanalytical Sciences to support drug discovery and DMPK research with LC-MS/MS bioanalysis of small molecules and PK analysis. The role involves bioanalytical data generation, PK reporting, formulation testing, and ADME-related activities to advance programs.

Ideal candidates will have hands-on LC-MS/MS experience, solid PK knowledge, and experience with biological matrices in a research setting.