Clinical Pharmacology Lead (Associate Director)

Scorpion Therapeutics; Pennsylvania; Hybrid; USD 180,000 - 240,000; Full time

Benefits offered by this job

Relocation assistance

Job summary

Pfizer is seeking a leader in clinical pharmacology to lead the pharmacology strategy for the Internal Medicine portfolio, focusing on model-informed drug development (MIDD) to advance efficient decision-making in early and late-stage programs.

The role involves cross-functional collaboration, integrating PK/PD data, designing dose regimens, supporting INDs and NDAs, and mentoring the team while staying current with regulatory guidance and scientific literature.

Qualifications

• MD/PhD or equivalent with 5+ years industry experience in clinical pharmacology, pharmacometrics, or systems pharmacology.
• Strong quantitative skills including experience with NONMEM, R, or similar tools; demonstrated leadership and cross-functional collaboration.
• Excellent communication abilities.
• Ability to travel periodically.

Responsibilities

• Design and oversee clinical pharmacology strategies
• Integrate PK/PD knowledge
• Contribute to clinical development plans
• Support regulatory submissions (IND, NDA/MAA)
• Collaborate with multifunctional teams; coach team members and stay current with literature and regulatory guidance

Job description

Role

Lead clinical pharmacology for Pfizer's Internal Medicine portfolio, focusing on model-informed drug development (MIDD) to support efficient drug discovery and decision-making.

Responsibilities

• design and oversee clinical pharmacology strategies
• integrate PK/PD knowledge
• contribute to clinical development plans
• support regulatory submissions (e.g., IND, NDA/MAA)
• Collaborate with multifunctional teams, ensuring appropriate dose and regimen selection through innovative modeling and analysis; coach team members, stay current with scientific literature and regulatory guidance; influence external scientific communities through publications and presentations.

Qualifications

• MD/PhD or equivalent with 5+ years industry experience in clinical pharmacology, pharmacometrics, or systems pharmacology
• strong quantitative skills including experience with NONMEM, R, or similar toolsdemonstrated leadership and cross‑functional collaboration skills
• excellent communication abilities
• ability to travel periodically

High-Value

Focus on small molecules or biologics in early to late-stage development within the Internal Medicine therapeutic area, emphasizing quantitative pharmacology and model-based approaches.

Work setup

• hybrid, based in the U.S., requiring onsite presence around 2.5 days/week.
• relocation assistance may be available.