Clinical Operations Manager

University of North Carolina - Chapel Hill; Lowell (MA); On-site; USD 90,000 - 130,000; Full time

Job summary

University of North Carolina at Chapel Hill is seeking a Clinical Operations Manager to oversee a large clinical research staff and ensure safe, compliant execution of oncology trials. You will report to the Assistant Director of Clinical Research Operations and coordinate resource allocation, data integrity, and SOP development.

Ideal candidates have advanced ICH GCP knowledge, extensive clinical research experience, and strong leadership abilities.

Qualifications

• Advanced knowledge of ICH GCP, Federal Regulations and Guidelines; following regulations, procedures and protocols.
• Clinical research experience.
• Experience in interviewing/hiring and performance management.
• Strong decision‑making and problem-solving skills.
• Excellent organizational skills with ability to manage large volumes of information.
• High level of accuracy and attention to detail.
• Comfort with technology and strong computer skills.
• Ability to plan work and coordinate multiple projects.

Responsibilities

• Oversee and manage clinical research staff across disease teams.
• Ensure safe, compliant, efficient conduct of oncology trials.
• Allocate resources and oversee research compliance and data integrity.
• Contribute to strategic planning, training, and SOP development.

Skills

ICH GCP

Clinical research

Hiring/Performance management

Decision making

Organization

Attention to detail

Tech savviness

Data documentation

Project coordination

Reports & SOPs

Interpersonal skills

Communication

Education

Master's degree in related field

Bachelor's degree + 2 years experience

Tools

Microsoft Office

EHR systems

Job description

Posting Information

• Department: LCCC - Clinical Trials-426806
• Career Area: Research Professionals
• Posting Open Date: 06/01/2026
• Application Deadline: 09/03/2026
• Open Until Filled: No
• Position Type: Permanent Staff (EHRA NF)
• Working Title: Clinical Operations Manager
• Appointment Type: EHRA Non-Faculty
• Position Number: 20076534, 20010901
• Vacancy ID: NF0009791
• Full Time/Part Time: Full-Time Permanent
• FTE: 1
• Hours per week: 40
• Position Location: North Carolina, US
• Hiring Range: Salary commensurate with qualifications
• Proposed Start Date: 06/29/2026

Position Information

A global higher education leader in innovative teaching, research and public service, the University of North Carolina at Chapel Hill consistently ranks as one of the nation's top public universities. Known for its beautiful campus, world-class medical care, commitment to the arts and top athletic programs, Carolina is an ideal place to teach, work and learn.

One of the best college towns and best places to live in the United States, Chapel Hill has diverse social, cultural, recreation and professional opportunities that span the campus and community.

University employees can choose from a wide range of professional training opportunities for career growth, skill development and lifelong learning and enjoy exclusive perks for numerous retail, restaurant and performing arts discounts, savings on local child care centers and special rates on select campus events. UNC-Chapel Hill offers full‑time employees a comprehensive benefits package, paid leave, and a variety of health, life and retirement plans and additional programs that support a healthy work/life balance.

Primary Purpose of Organizational Unit

Our mission is to improve the health and well‑being of North Carolinians and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education and research.

Patient care: We promote health and provide superb clinical care while maintaining our strong tradition of reaching underserved populations and reducing health disparities across North Carolina and beyond.

Education: We prepare tomorrow`s healthcare professionals and biomedical researchers from all backgrounds by facilitating learning within innovative and integrated curricula and team‑oriented interprofessional education to ensure a highly skilled workforce.

Research: We develop and support a rich array of outstanding health sciences research programs, centers and resources. We provide infrastructure and opportunities for collaboration among disciplines throughout and beyond our university to support outstanding research. We foster programs in the areas of basic, translational, mechanistic and population research.

Position Summary

The Clinical Operations Manager provides oversight and management of a large number of clinical research staff to ensure safe, compliant, efficient, and effective conduct of oncology clinical trials. This position provides expert level knowledge in clinical trial practices and regulations. This position works under the direct supervision of the Assistant Director of Clinical Research Operations to ensure safe implementation of oncology clinical trials. The Clinical Operations Manager manages clinical research staff assigned to various disease teams within the Clinical Protocol Office (CPO) providing daily management/supervision, resource and effort allocation, overseeing research compliance and data integrity, and assisting in strategic planning and operational support. This position creates and champions a collaborative and positive relationship dynamic with internal staff and external agencies/organizations.

Minimum Education and Experience Requirements

Master's degree in a discipline related to the field assigned; or Bachelor's degree in a discipline related to the field assigned and two years of research/analysis, preferably with one year in a supervisory role; or equivalent combination of training and experience. All degrees must be received from appropriately accredited institutions.

Required Qualifications, Competencies, and Experience

• Advanced knowledge of ICH GCP, Federal Regulations and Guidelines and ability to follow established regulations, procedures, and protocols
• clinical research experience
• Experience in interviewing/hiring process and performance management
• Possess strong decision‑making skills and the ability to problem solve and troubleshoot issues
• Strong organizational skills with the ability to manage large volumes of information
• High level of accuracy and attention to detail
• High level of comfort with technology
• Strong computer skills
• Ability to gather data and document procedures
• Ability to plan work and coordinate multiple projects
• Ability to contribute to preparation and delivery of reports, trainings and SOPs
• Customer oriented and ability to work within, build and lead a team
• Exceptional interpersonal skills and excellent verbal and written communication skills in daily interactions with the ability to interpret and apply UNC policies and federal, state, and local regulations
• Ability to work on evenings, weekends and/or holidays occasionally required

Preferred Qualifications, Competencies, and Experience

• Therapeutic clinical trial coordination experience involving drugs and/or devices, to include work in oncology
• SOCRA/ACRP certification
• Supervisory experience
• Experience in Phase I, II, and III clinical research
• Experience navigating medical records and data extraction
• Experience leading a large team

Campus Security Authority Responsibilities

Not Applicable.

Quick Link

https://unc.peopleadmin.com/postings/319826

Posting Contact Information

• Department Contact Name and Title: Gretchen Harrison
• Department Contact Telephone or Email: [e-mail]
• Office of Human Resources Contact Information: If you experience any problems accessing the system or have questions about the application process, please contact the Office of Human Resources at [phone] or send an email to [e-mail]. Please note: The Office of Human Resources will not be able to provide specific updates regarding position or application status.

Equal Opportunity Employer Statement

The University is an equal opportunity employer and welcomes all to apply without regard to age, color, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, or sexual orientation. We encourage all qualified applicants to apply, including protected veterans and individuals with disabilities.