Clinical Operations Manager

University of North Carolina at Chapel Hill; Chapel Hill (NC); On-site; USD 95,000 - 130,000; Full time

Job summary

University of North Carolina at Chapel Hill is seeking a Clinical Operations Manager to oversee oncology clinical trials, ensure regulatory compliance, and coordinate a large clinical research staff. The role supports trial operations, data integrity, and process improvement within the Clinical Protocol Office.

The position requires strong leadership, ICH GCP knowledge, and experience in project management.

Qualifications

• Advanced knowledge of ICH GCP, Federal Regulations and Guidelines and ability to follow established regulations, procedures, and protocols.

Responsibilities

• Oversee and manage a large number of clinical research staff to ensure safe, compliant, efficient, and effective conduct of oncology clinical trials.
• Provide daily management, resource and effort allocation, oversight of research compliance and data integrity, and assist in strategic planning.
• Foster collaborative relationships with internal staff and external agencies/organizations.

Skills

ICH GCP & Regulations

Clinical Research Experience

Hiring & Performance Mgmt

Decision-making & Troubleshooting

Data Management

Project Coordination

Communication

Tech Proficiency

Team Leadership

Attention to Detail

Education

Master's degree in related field

Bachelor's degree in related field + 2 years experience

Tools

Electronic data capture systems

Job description

Department

LCCC - Clinical Trials-426806

Career Area

Research Professionals

Posting Open Date

06/01/2026

Application Deadline

09/03/2026

Open Until Filled

No

Position Type

Permanent Staff (EHRA NF)

Working Title

Clinical Operations Manager

Appointment Type

EHRA Non-Faculty

Position Number

20076534, 20010901

Vacancy ID

NF0009791

Full Time/Part Time

Full-Time Permanent

FTE

1

Hours per week

40

Position Location

North Carolina, US

Hiring Range

Salary commensurate with qualifications

Proposed Start Date

06/29/2026

Be a Tar Heel!

A global higher education leader in innovative teaching, research and public service, the University of North Carolina at Chapel Hill consistently ranks as one of the nation’s top public universities. Known for its beautiful campus, world-class medical care, commitment to the arts and top athletic programs, Carolina is an ideal place to teach, work and learn.One of the best college towns and best places to live in the United States, Chapel Hill has diverse social, cultural, recreation and professional opportunities that span the campus and community.University employees can choose from a wide range of professional training opportunities for career growth, skill development and lifelong learning and enjoy exclusive perks for numerous retail, restaurant and performing arts discounts, savings on local child care centers and special rates on select campus events. UNC-Chapel Hill offers full-time employees a comprehensive benefits package, paid leave, and a variety of health, life and retirement plans and additional programs that support a healthy work/life balance.

Primary Purpose of Organizational Unit

Our mission is to improve the health and well-being of North Carolinians and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education and research.

Patient care: We promote health and provide superb clinical care while maintaining our strong tradition of reaching underserved populations and reducing health disparities across North Carolina and beyond.

Education: We prepare tomorrow`s healthcare professionals and biomedical researchers from all backgrounds by facilitating learning within innovative and integrated curricula and team-oriented interprofessional education to ensure a highly skilled workforce.

Research: We develop and support a rich array of outstanding health sciences research programs, centers and resources. We provide infrastructure and opportunities for collaboration among disciplines throughout and beyond our university to support outstanding research. We foster programs in the areas of basic, translational, mechanistic and population research.

Position Summary

The Clinical Operations Manager provides oversight and management of a large number of clinical research staff to ensure safe, compliant, efficient, and effective conduct of oncology clinical trials. This position provides expert level knowledge in clinical trial practices and regulations. This position works under the direct supervision of the Assistant Director of Clinical Research Operations to ensure safe implementation of oncology clinical trials. The Clinical Operations Manager manages clinical research staff assigned to various disease teams within the Clinical Protocol Office (CPO) providing daily management/supervision, resource and effort allocation, overseeing research compliance and data integrity, and assisting in strategic planning and operational support. This position creates and champions a collaborative and positive relationship dynamic with internal staff and external agencies/organizations.

Minimum Education and Experience Requirements

Master’s degree in a discipline related to the field assigned; or Bachelor’s degree in a discipline related to the field assigned and two years of research/analysis, preferably with one year in a supervisory role; or equivalent combination of training and experience. All degrees must be received from appropriately accredited institutions.

Required Qualifications, Competencies, and Experience

Advanced knowledge of ICH GCP, Federal Regulations and Guidelines and ability to follow established regulations, procedures, and protocols; clinical research experience; Experience in interviewing/hiring process and performance management; Possess strong decision-making skills and the ability to problem solve and troubleshoot issues; Strong organizational skills with the ability to manage large volumes of information; High level of accuracy and attention to detail; High level of comfort with technology; Strong computer skills; Ability to gather data and document procedures; Ability to plan work and coordinate multiple projects; Ability to contribute to preparation and delivery of reports, trainings and SOPs; Customer oriented and ability to work within, build and lead a team; Exceptional interpersonal skills and excellent verbal and written communication skills in daily interactions with the ability to interpret and apply UNC policies and federal, state, and local regulations; Ability to work on evenings, weekends and/or holidays occasionally required.

Preferred Qualifications, Competencies, and Experience

• Therapeutic clinical trial coordination experience involving drugs and/or devices, to include work in oncology;
• SOCRA/ACRP certification;
• Supervisory experience;
• Experience in Phase I, II, and III clinical research;
• Experience navigating medical records and data extraction;
• Experience leading a large team.

Campus Security Authority Responsibilities

Not Applicable.