Chief of Staff - AI Bio Ops & Strategy Leader

Broaden Management Partners; San Francisco (CA); On-site; USD 108,000 - 132,000; Full time

Benefits offered by this job

Equity

Job summary

Broaden Management Partners is seeking a Chief of Staff for a San Francisco, in-person role to serve as the core operational engine across a fast-moving AI and frontier enzyme design startup. You will partner with the CEO, bridge cross-functional teams, and lead zero-to-one initiatives that translate research breakthroughs into organizational momentum.

This autonomous generalist role requires removing bottlenecks, structuring execution, and maintaining operational rigor to design and test new

Qualifications

• Ability to translate ambiguous challenges into concrete plans with minimal direction.
• Strong interest in biotechnology, AI/ML, computational science.
• Clear, structured written and verbal communication; executive summaries.

Responsibilities

• Establish internal operating systems with founders and track cross-team deliverables.
• Bridge workflows between computational modelling, data engineering, and wet-lab feedback loops.
• Own high-priority initiatives, including hiring workflows, partnerships, and vendor operations.
• Support investor relations, external communications, and board materials preparation.
• Manage day-to-day operations, facilities, procurement, and team tooling.

Skills

Synthesize complex problems

AI/ML curiosity

Clear communication

Proactive builder

Judgment & prioritization

Job description

Broaden Management Partners is seeking a Chief of Staff for a San Francisco, in-person role to serve as the core operational engine across a fast-moving AI and frontier enzyme design startup. You will partner with the CEO, bridge cross-functional teams, and lead zero-to-one initiatives that translate research breakthroughs into organizational momentum.

This autonomous generalist role requires removing bottlenecks, structuring execution, and maintaining operational rigor to design and test new