Cell Engineering Scientist: Primary Cells & CRISPR

Colossal Biosciences; Dallas (TX); On-site; USD 110,000 - 130,000; Full time

Benefits offered by this job

Medical, dental, and vision coverage

Relocation assistance

Flexible spending accounts (FSA)

Company matched 401k retirement plan

Paid parental leave at 100% salary for

Education reimbursement

Job summary

Colossal Biosciences is hiring a Scientist to derive primary cell lines from non-model organisms, perform gene editing, and deliver edited lines for SCNT. Based in Dallas, TX, you will join the CEP core team and report to the Manager of Primary Cell and Production.

You will work with colleagues to optimize cell lines and participate in gene editing workflows, with an emphasis on rigorous documentation and collaboration in a fast-paced startup environment.

Qualifications

• PhD or equivalent in a relevant biological field; BS/MS with substantial experience considered.
• 4+ years hands-on mammalian cell culture experience.
• Expert CRISPR editing with multiple delivery methods.
• Experience with flow cytometry, immunostaining, and confocal microscopy.
• Strong written and oral communication; problem-solving skills.

Responsibilities

• Isolate, expand, and maintain high-quality primary cell cultures from diverse non-model animal tissues.
• Innovate and execute experiments to derive primary cells from non-model mammals; develop functional assays.
• Assess workflow efficiency via cellular assays and NGS sequencing.
• Collaborate with genome engineers to screen, validate, and make cell lines for SCNT.
• Work on project milestones.
• Attend lab meetings, prepare reports and presentations.
• Maintain excellent laboratory records.

Skills

Primary cell culture

CRISPR gene editing

Flow cytometry

Immunostaining

Confocal microscopy

Microdissection

Aseptic technique

Communication skills

Problem solving

Teamwork

Organizational skills

Attention to detail

Emotional intelligence

Analytical skills

Education

PhD in biological sciences, stem cell biology, genetics or related field

Job description

Colossal Biosciences is hiring a Scientist to derive primary cell lines from non-model organisms, perform gene editing, and deliver edited lines for SCNT. Based in Dallas, TX, you will join the CEP core team and report to the Manager of Primary Cell and Production.

You will work with colleagues to optimize cell lines and participate in gene editing workflows, with an emphasis on rigorous documentation and collaboration in a fast-paced startup environment.