Bioprocess Engineer: Scale-Up & Process Optimization

Placements24; Riverton (UT); On-site; USD 54,000 - 79,000; Full time

Job summary

Placements24 seeks a Bioprocess Engineer for a cutting-edge biopharmaceutical manufacturing facility in Upington, Northern Cape. The role focuses on developing, optimizing, and scaling bioprocesses to produce high-quality therapeutic products.

You will lead upstream and downstream process development, drive scale-up activities from lab to production scales, and ensure documentation and validation comply with GMP and global regulatory standards.

Qualifications

• Design, develop, and optimize upstream (cell culture, microbial) and downstream (purification) bioprocesses for therapeutic products.
• Lead scale-up activities from lab to pilot and commercial scales.
• Develop and execute process validation protocols and generate reports in compliance with regulatory requirements (GMP, FDA, EMA).
• Troubleshoot process deviations and implement CAPA actions.
• Author and review technical documents including process descriptions and batch records.

Responsibilities

• Design, develop, and optimize upstream (cell culture, microbial fermentation) and downstream (purification) bioprocesses for therapeutic products.
• Lead scale-up activities from laboratory bench to pilot and commercial manufacturing scales.
• Develop and execute process validation protocols and generate reports in compliance with regulatory requirements (GMP, FDA, EMA).
• Troubleshoot process deviations and implement effective CAPA actions.
• Author and review technical documents, including process descriptions and batch records.

Skills

Bioprocess Engineering

Process Scale-Up

GMP Compliance

Tools

Cell Culture

Downstream Purification

Job description

Placements24 seeks a Bioprocess Engineer for a cutting-edge biopharmaceutical manufacturing facility in Upington, Northern Cape. The role focuses on developing, optimizing, and scaling bioprocesses to produce high-quality therapeutic products.

You will lead upstream and downstream process development, drive scale-up activities from lab to production scales, and ensure documentation and validation comply with GMP and global regulatory standards.