Biopharmaceutical Production Scientist

Placements24; Riverton (UT); On-site; USD 29,000 - 44,000; Full time

Job summary

Placements24 is seeking a Biopharmaceutical Production Scientist for a cutting-edge biopharma company based in Upington, Northern Cape. The role focuses on large-scale manufacturing of monoclonal antibodies and recombinant proteins, involving upstream cell culture and downstream purification while adhering to strict GMP standards.

You will work with mammalian cell culture processes, purification technologies, and production equipment in a state-of-the-art facility.

Qualifications

• Strong scientific background in cell biology, biochemistry, or bioprocess engineering.
• Hands-on experience in biopharmaceutical manufacturing.
• Familiarity with GMP standards and regulatory requirements.

Responsibilities

• Execute and monitor mammalian cell culture processes for biologics production.
• Perform downstream purification operations to isolate and purify target proteins.
• Operate and maintain production equipment with proper calibration.
• Follow SOPs and batch records to ensure quality and traceability.
• Perform in-process testing and data analysis to monitor performance.
• Support process troubleshooting and optimization activities.
• Ensure compliance with GMP, safety, and environmental standards.
• Maintain detailed production records and documentation.
• Support process validation activities.

Skills

Cell culture

Bioprocess knowledge

GMP compliance

Tools

Chromatography

Filtration

Job description

About the Role

Our client, a cutting-edge biopharmaceutical company at the forefront of therapeutic innovation, is seeking a highly skilled Biopharmaceutical Production Scientist to join their team in **Upington, Northern Cape**. This role is essential for the large-scale manufacturing of complex biological products, including monoclonal antibodies and recombinant proteins. You will be involved in upstream (cell culture) and/or downstream (purification) processes, ensuring adherence to strict GMP standards and regulatory requirements. The ideal candidate possesses a strong scientific background in cell biology, biochemistry, or bioprocess engineering, coupled with hands‑on experience in biopharmaceutical manufacturing. This is a significant opportunity to contribute to the production of life‑changing biotherapeutics in a state‑of‑the‑art facility in **Upington**.

Key Responsibilities

• Execute and monitor mammalian cell culture processes (e.g., bioreactors, wave bags) for the production of biologics.
• Perform downstream purification operations (e.g., chromatography, filtration) to isolate and purify target proteins.
• Operate and maintain production equipment, ensuring proper calibration and functionality.
• Follow Standard Operating Procedures (SOPs) and batch records meticulously to ensure product quality and consistency.
• Perform in‑process testing and data analysis to monitor process performance.
• Participate in process troubleshooting and optimization activities.
• Ensure compliance with GMP, safety regulations, and environmental standards.
• Maintain accurate and detailed production records and documentation.
• Support process validation activities and technology