Bioanalytical Scientist, DACs & LC-MS/MS PK/PD

Nurix Therapeutics; Brisbane (CA); On-site; USD 90,000 - 130,000; Full time

Job summary

Nurix Therapeutics seeks a Scientist to lead bioanalytical strategies for next-generation degrader antibody conjugates (DACs). The role emphasizes LC-MS/MS and hybrid assays to analyze bioconjugates across in vitro and in vivo studies, shaping understanding of pharmacokinetics, pharmacodynamics and biotransformation.

The candidate will work at the interface of small and large molecule bioanalysis, contribute to assay development and method qualification, and collaborate with discovery and early

Qualifications

• Experience leading LC-MS/MS bioanalytical assays.
• In vitro and in vivo study support.
• Assay development and qualification.

Responsibilities

• Lead bioanalytical strategies for DACs.
• Develop and qualify LC-MS/MS and hybrid assays.
• Characterize pharmacokinetics, pharmacodynamics, and biotransformation.
• Collaborate across discovery and development teams.

Skills

LC-MS/MS

Hybrid assays

Bioanalysis

Pharmacokinetics

Tools

Mass spectrometry

Job description

Nurix Therapeutics seeks a Scientist to lead bioanalytical strategies for next-generation degrader antibody conjugates (DACs). The role emphasizes LC-MS/MS and hybrid assays to analyze bioconjugates across in vitro and in vivo studies, shaping understanding of pharmacokinetics, pharmacodynamics and biotransformation.

The candidate will work at the interface of small and large molecule bioanalysis, contribute to assay development and method qualification, and collaborate with discovery and early