B-Cell Immunology Scientist — Translational Research

Proclinical Group; Palo Alto (CA); On-site; USD 140,000 - 200,000; Full time

Job summary

Proclinical Group is seeking a Scientist specializing in B-Cell Biology to join a dynamic team in Palo Alto, CA. The successful candidate will support preclinical immunology research, design and execute experiments, and collaborate with cross-functional teams to advance programs.

Responsibilities include in vitro pharmacology work, in vivo studies with CRO partners, data analysis, and mentoring staff. A PhD (or MS with relevant experience) in immunology or related field is required.

Qualifications

• Advanced degree (PhD) in Immunology or a related life sciences discipline, or an MS with relevant laboratory experience.
• Expertise in B-cell biology and/or autoimmune disease is preferred.
• Proficiency in techniques such as primary human/animal tissue handling, cell culture, ELISAs/MSDs, flow cytometry, nucleic acid isolation, and qRT-PCR.
• Familiarity with RNA-seq and/or scRNA-seq data analysis is a plus.
• Strong organizational, problem-solving, and communication skills.
• Experience with Microsoft Office (Word, Excel, PowerPoint) and collaboration tools (Zoom, Teams, Box).
• Knowledge of electronic laboratory notebooks (e.g., Benchling) and GraphPad Prism is preferred.
• Highly organized and precise in laboratory practices and maintenance.

Responsibilities

• Conduct and support translational studies for preclinical programs.
• Perform hands-on in vitro pharmacology experiments and maintain cell cultures.
• Design and oversee in vivo pharmacology studies with CRO partners.
• Manage laboratory reagents, organization, storage, and disposal.
• Collaborate with the team to maintain lab space, equipment, and inventory.
• Record data, prepare technical reports, and summarize findings.
• Communicate project progress to supervisors.
• Develop and implement new assays, execute experiments, and analyze data of moderate complexity.
• Provide guidance and mentorship to staff, researchers, or interns.
• Manage timelines to meet project goals and deliverables.
• Present findings at internal meetings.
• Collaborate with cross-functional teams to support research needs.

Skills

B-cell biology

Autoimmune disease

Cell culture

Flow cytometry

ELISA/MSD

qRT-PCR

RNA-seq / scRNA-seq analysis

Tissue handling

Organizational skills

Communication

Problem-solving

Education

PhD in Immunology or related

MS with relevant laboratory experience

Tools

Benchling

GraphPad Prism

Box

Zoom

Microsoft Teams

Excel

PowerPoint

Job description

Proclinical Group is seeking a Scientist specializing in B-Cell Biology to join a dynamic team in Palo Alto, CA. The successful candidate will support preclinical immunology research, design and execute experiments, and collaborate with cross-functional teams to advance programs.

Responsibilities include in vitro pharmacology work, in vivo studies with CRO partners, data analysis, and mentoring staff. A PhD (or MS with relevant experience) in immunology or related field is required.