AVP/ Head, Quantitative Pharmacology & Pharmacometrics - Oncology

Scorpion Therapeutics; Pennsylvania; Hybrid; USD 230,000 - 320,000; Full time

Job summary

Scorpion Therapeutics seeks a Head of Quantitative Pharmacology & Pharmacometrics (QP2) to lead oncology drug development strategy, integrating modeling to inform dosing, safety, efficacy, and portfolio decisions.

The role requires a PhD with 15+ years in drug development, including 5+ in oncology, with expertise across modalities and leadership of interdisciplinary teams. Hybrid work with flexible location is offered.

Qualifications

• Ph.D. with 15+ years in drug development, including oncology
• Experience leading cross-functional QP2 initiatives
• Proven record of regulatory submissions and translational science

Responsibilities

• Establish enterprise QP2 strategy and oversee the team
• Shape program design and guide regulatory interactions
• Develop a modern quantitative operating model for oncology

Skills

Pharmacometric modeling

Model-informed development

Regulatory strategy

Team leadership

Education

PhD in Pharmacology

Tools

NONMEM

R

Python

Monolix

Job description

Role

Head of Quantitative Pharmacology & Pharmacometrics (QP2) to lead oncology drug development strategy, integrating advanced analytics and modeling to inform dosing, safety, efficacy, and portfolio decisions.

Responsibilities

establish enterprise QP2 strategy, oversee team, shape program design, guide regulatory interactions, and develop a modern quantitative operating model for oncology.

Requirements

Ph.D. with 15+ years in drug development, including 5+ years in oncology, with expertise across modalities like ADCs, small molecules, TCEs, and biologics.

Demonstrated impact in model-informed drug development, regulatory submissions, and leadership of interdisciplinary teams.

High-Value

High-Value: oncology, multiple modalities, regulatory filings (NDA/MAA), advanced modeling techniques, application of AI/ML, and translational sciences.

WorkSetup

hybrid with flexible location; no specific travel noted.