Director, Quantitative Clinical Pharmacology: PK/PD Modeling & Strategy

Scorpion Therapeutics; Illinois; Hybrid; USD 230,000 - 320,000; Full time

Job summary

Scorpion Therapeutics is seeking a Director of Quantitative & Clinical Pharmacology to lead clinical pharmacology and pharmacometrics from early development through late-stage trials and registration. You will develop quantitative strategies, oversee PK/PD modeling, support dose selection, and help shape regulatory strategies, collaborating with cross-functional teams in a hybrid U.S.

work setup. This role requires a PhD and 7+ years, with NONMEM and R expertise, and offers impactful work at the

Qualifications

• PhD required in pharmaceutical sciences, mathematics, engineering, or a related field.
• 7+ years of experience in clinical pharmacology or pharmacometrics.
• Strong PK/PD modeling expertise, with NONMEM and R proficiency.
• Translational and regulatory strategy experience is desirable.

Responsibilities

• Develop and execute quantitative pharmacology strategies.
• Lead model-based analyses including PK/PD modeling and meta-analyses.
• Support clinical dose selection.
• Contribute to regulatory strategies and engagements.

Skills

Quantitative pharmacology

Clinical pharmacology

Model-based analyses

Education

PhD in Pharmaceutical Sciences, Mathematics, Engineering, or related field

Tools

NONMEM

R

Job description

Role

Director of Quantitative & Clinical Pharmacology, leading clinical pharmacology and pharmacometrics activities from early development through late-stage trials and registration.

Responsibilities

• develop and execute quantitative pharmacology strategies
• lead model-based analyses (PK/PD modeling, meta-analyses, disease modeling)
• support clinical dose selection
• contribute to regulatory strategies and engagements

Requirements

• PhD in Pharmaceutical Sciences, Mathematics, Engineering, or related field;
• 7+ years in clinical pharmacology or pharmacometrics;
• strong expertise in PK/PD modeling, with proficiency in NONMEM and R preferred.

HighValue

focus on clinical dose refinement, predictive modeling, and translational approaches; experience with siRNA or CNS therapeutics is advantageous.

WorkSetup

hybrid in the U.S., with some on-site presence and occasional in-person events.