Associate Scientist, Purification Process

ThermoFisher Scientific; Wilmington (DE); On-site; USD 65,000 - 85,000; Full time

Benefits offered by this job

Annual incentive plan bonus

Healthcare

Employee benefits

Job summary

Thermo Fisher Scientific in Wilmington, DE is seeking an Associate Scientist, Purification Process Science to support downstream process development for therapeutic monoclonal antibodies and bispecifics, on a fully onsite basis at the customer site.

The role emphasizes purification process development, optimization, scale-up, and analytical support, with responsibilities including protein purification, buffer prep, in-process analysis, and collaboration with formulation and cell culture teams.

Qualifications

• BS or MS in biochemistry, bioengineering, biology, chemistry or related field, preferably with up to 2 years of relevant industry experience.
• Equivalency may be considered with education, training and/or related experience.
• Basic knowledge in protein chemistry and bioprocessing.
• Hands-on experiences in chromatography (affinity, size exclusion, ion exchanges, multi-mode) and filtration.
• Experience with protein analysis methods (HPLC, ELISA, pH/Conductivity/A280).
• Experience with ultrafiltration/diafiltration is preferred.
• Strong communication and organizational skills.

Responsibilities

• Perform or aid in purification process development, optimization, and scale-up manufacturing.
• Support formulation team's material needs and cell culture development.
• Perform routine analyses of in-process samples using relevant product purity and process impurity analytical tools.
• Prepare buffers and solutions needed for laboratory work.
• Present work summary in a weekly group meeting.
• Write routine electronic laboratory notebook entries.
• Other responsibilities as assigned.

Skills

Protein purification knowledge

Bioprocessing basics

Communication skills

Organized, collaborative

Team-oriented

Education

BS or MS in biochemistry/biology/chemistry or related field

Tools

HPLC

ELISA

TFF systems

Filtration technology

pH/Conductivity/A280 testing

Job description

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Laboratory Setting

Job Description

Associate Scientist, Purification Process Science

Job Title: Associate Scientist, Purification Process

This is a fully onsite role based at our customer's site in Wilmington, DE. We welcome applicants from all locations within the US. Please note that relocation assistance is not provided for this position, and any relocation costs will be the responsibility of the candidate.

Must be legally authorized to work in the United States withoutsponsorship.

Must be able to pass a comprehensive background check, whichincludes a drug screening.

At Thermo Fisher Scientific, you'll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life - enabling our customers to make the world healthier, cleaner and safer. We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through research, development and delivery of life-changing therapies. With clinical trials conducted in 100+ countries and ongoing development of novel frameworks for clinical research through our PPD clinical research portfolio, our work spans laboratory, digital and decentralized clinical trial services. Your determination to deliver quality and accuracy will improve health outcomes that people and communities depend on - now and in the future.

Thermo Fisher's clinical research business is a leading global contract research organization and world leader in serving science. We are passionate, deliberate, and driven by our mission - to enable our customers to make the world healthier, safer, and cleaner.

Our Laboratories Functional Service Partnership (FSP) team plays a direct role in advancing drug development by creating sustained groups of talent within our customers' organizations to provide long-term support. Through this collaborative approach, our professionals bring their commitment to excellence, industry knowledge, and operational strength directly into customer environments, helping to enhance capabilities and advance the delivery of life-changing therapies.

Job Summary:

Our Client is seeking a motivated and dedicated protein purification scientist to support downstream process development and optimization, primarily for novel therapeutic monoclonal antibody and bispecific products throughout all stages of the clinical lifecycle.

Key Responsibilities

• Perform or aid in purification process development, optimization, and scale-up manufacturing

• Conduct protein purification to support formulation team's material needs and cell culture development

• Perform routine analyses of in-process samples using relevant product purity and process impurity analytical tools

• Prepare buffers and solutions needed for laboratory work

• Present work summary in a weekly group meeting

• Write routine electronic laboratory notebook entries

• Other responsibilities as assigned

Education and Experience

BS or MS degree in biochemistry, bioengineering, biology, chemistry or related field, preferably with up to 2 years of relevant industry experience

In some cases an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.

Knowledge, Skills and Abilities:

• Basic knowledge in protein chemistry and bioprocessing

• Basic knowledge and preferably hands-on experiences in various types of column/membrane chromatography (affinity, size exclusion, ion exchanges, multi-mode) and filtration technology

• Experience in protein analysis such as HPLC, ELISA, pH/Conductivity/A280 Concentration testing, etc. is preferred

• Hands-on experience or basic knowledge of Ultrafiltration/Diafiltration experimentation and TFF systems is preferred

• Inventory management skills preferred

• Good verbal and written communication skills

• Organized, collaborative, independent, meticulous

Working Environment:

Below is listed the working environment/requirements for this role:

Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.

Able to work upright and stationary and/or standing for typical working hours.

Able to lift and move objects up to 25 pounds

Able to work in non-traditional work environments.

Able to use and learn standard office equipment and technology with

proficiency.

May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments.

Able to perform successfully under pressure while prioritizing and handling multiple projects or activities.

Benefits

We offer competitive remuneration, annual incentive plan bonus, healthcare, and a range of employee benefits. Thermo Fisher Scientific offers employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer an exciting company culture that stands for integrity, intensity, involvement, and innovation!

Why Join Us?

When you join Thermo Fisher Scientific, you become part of a global team that values passion, innovation, and a commitment to scientific excellence. You'll work in an environment where collaboration and development are part of the everyday experience - and where your contributions truly make a difference.

Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.