Associate Scientist, Process Development Downstream

Avid Bioservices; Tustin (CA); On-site; USD 94,000 - 118,000; Full time

Job summary

Avid Bioservices, a biopharmaceutical CDMO, invites an Associate Scientist to design and optimize downstream purification processes for monoclonal antibody development. The role emphasizes transfer to manufacturing and cross-functional collaboration to meet clinical and commercial program goals.

Will contribute to experimental design, data analysis, and documentation for regulatory filings, with regular communication to teams and potential client interactions.

Qualifications

• PhD with preferred 2 years of process development experience.
• Master's with minimum 2 years; preferred 4 years of process development and/or similar experience.
• Bachelor's with minimum 4 years; preferred 6 years of process development and/or similar experience.

Responsibilities

• Designs, optimizes, scales and transfers downstream processes for mAb development programs.
• Performs bench-scale experiments across the end-to-end downstream drug substance process.
• Applies scientific and engineering principles to purification processes to support development and characterization.
• Designs experiments and analyzes results to draw meaningful conclusions.
• Communicates findings through oral presentations and GMP-compliant reports for regulatory filings.
• Collaborates with Process Development, Project Management, Manufacturing, and Quality to implement viable solutions.

Education

PhD in Life Sciences

Master's in Life Sciences

Bachelor's in Life Sciences

Job description

Looking to join a passionate team dedicated to developing and manufacturing life-saving biopharmaceuticals? Avid Bioservices is a leading clinical and commercial biologics CDMO focused on creating innovative solutions to meet the needs of our clients and improve patient outcomes.

Your Role:

Within Process Development, the Associate Scientist, Process Development - Downstream in the Purification Process Development lab will design, optimize scales and transfer downstream processes for mAb development programs.

Key Responsibilities:

• Applies established platform approaches and utilizes problem-solving skills to rapidly solve day- to day experimental challenges.
• Performs experiments at the bench scale, spanning the end-to-end downstream drug substance process.
• Applies fundamental scientific and engineering principles to purification processes to support process development and process characterization, evaluate process improvements and resolve potential processing issues.
• Designs suitable experiments and analyzes results to draw meaningful conclusions.
• Communicates work through oral presentations and written documentation including technical reports and GMP documents to support regulatory filings.
• Participate with cross-functional teams and interact with representatives from Process Development, Project Management, Manufacturing, and Quality to arrive at and implement viable/practical solutions to support clinical/commercial manufacturing.
• Provides scientific technical support for technology transfer of processes to manufacturing.
• Demonstrates the desire to expand and develop skills in purification.
• Utilizes out-of-the-box thinking to contribute to technology development.
• Familiarity with design of experiments and statistical analysis of data.
• May be the primary project contact with a client and must be able to articulate the science and problem solving.
• May supervise laboratory assistants or research associates but primarily would be an individual contributor.
• Other duties may be assigned.

Minimum Qualifications:

• PhD degree, with preferred 2 years of process development and/or similar experience or:
• Master's degree and minimum 2 years; with preferred 4 years of process development and/or similar experience or:
• Bachelor's degree and minimum of 4 years; preferred 6 years of process development and/or similar experience.

Preferred Qualifications:

• Process development experience.

Position Type/Expected Hours of Work:

This role is a full-time position. Days and hours of work are Monday through Friday, 8:00 a.m. to 5 p.m. unless otherwise stated by Supervisor. The employee must also, if instructed, have the ability to work overtime and/or weekends when necessary.

Compensation:

We offer competitive compensation packages for this role, including a base salary, performance-based bonuses, and comprehensive benefits such as health, dental, and vision insurance, 401(k) matching, and paid time off.

The compensation range for this role is $94,400 - $118,000 annually, depending on experience and qualifications. Additionally, we offer opportunities for career growth and development as well as a supportive and inclusive work environment.

Who you are:

• You have a "bring it on!" team player approach and an unshakable positive attitude, always ready to tackle anything that comes your way.
• Your written and verbal skills are out of this world, and you communicate with clarity and confidence.
• You have exceptional multitasking skills and an unparalleled attention to detail that ensure the smooth running of everything.
• You are a master at building relationships, capable of establishing connections with anyone, be it team members, clients, vendors, or suppliers.

Physical Demands & Work Environment:

In this dynamic role, expect a blend of regular activities like sitting, standing, and walking, with occasional physically engaging tasks such as lifting objects up to 20 pounds. The work environment might expose you to electrical shocks, toxic chemicals, vibrations, or loud noise levels occasionally. However, reasonable accommodations are available to enable individuals with different abilities to perform effectively, ensuring a supportive and adaptable work setting. Your visual acuity, including close, distance, and color vision, will be essential in navigating through the diverse day-to-day demands of this position.