Associate Scientist, Protein Characterization

Scorpion Therapeutics; Bridgewater (MA); On-site; USD 103,000 - 131,000; Full time

Job summary

Scorpion Therapeutics is seeking a scientist to support formulation and characterization of biotherapeutic drug products across therapeutic areas. You will perform protein analytical techniques to optimize formulation and process in support of development candidate nomination.

The role focuses on assessing stability as a function of formulation and process and facilitating tech transfer. Strong communication and cross-functional collaboration are essential in this in-person, full-time position

Qualifications

• Solid understanding of protein biotherapeutics, especially stability and formulation challenges.
• Experience analyzing proteins using standard analytical and/or biophysical techniques.
• Knowledge/interest in advanced analytical & biophysical techniques: DLS, SEC-MALS, batch MALS, circular dichroism, fluorescence, Amide IFTIR, DSC thermal stability, sub-visible particle analysis.

Responsibilities

• Support formulation and characterization of biotherapeutic drug product discovery and development across therapeutic areas.
• Perform protein analytical techniques to optimize formulation and process to support development candidate nomination.
• Assess biotherapeutic stability as a function of formulation and process and facilitate tech transfer.

Skills

Protein biotherapeutics stability

Formulation challenges

Analytical techniques for proteins

DLS

SEC-MALS

Circular dichroism

Fluorescence spectroscopy

DSC thermal stability

Amide IFTIR

Sub-visible particle analysis

Electronic lab notebooks

Communication

Detail-oriented

Collaboration

Education

B.S. in Biochemistry/related

M.S. in related field

Tools

AKTA FPLC

Job description

Responsibilities:

• Support formulation and characterization of biotherapeutic drug product discovery and development across therapeutic areas.
• Perform protein analytical techniques to optimize formulation and process to support development candidate nomination.
• Assess biotherapeutic stability as a function of formulation and process and facilitate tech transfer.

Qualifications:

• Bachelor's degree in Biochemistry, Biotechnology, Chemical Engineering, Bioengineering, Pharmaceutical Sciences (or related) with 4+ years relevant hands-on experience; or Master's degree with 3+ years.

Skills/Experience:

• Solid understanding of protein biotherapeutics, especially stability and formulation challenges.
• Experience analyzing proteins using standard analytical and/or biophysical techniques.
• Knowledge/interest in advanced analytical & biophysical techniques: DLS, SEC-MALS, batch MALS, circular dichroism, fluorescence, Amide IFTIR, DSC thermal stability, sub-visible particle analysis.
• Familiarity with electronic lab notebooks; strong written/oral communication.
• Detail-oriented, highly organized, able to multi-task.
• Demonstrate Collaboration, Accountability, Passion, Respect, and Integrity; interact effectively in a dynamic, culturally diverse workplace.

Nice to have:

• Automated chromatography workstations (e.g., AKTA FPLCs) and multi-dimensional purification; scientific publications.

Where/Travel:

• Bridgewater, NJ; full-time, in-person. Minimal travel.

Pay Range: $103,000-$131,000 annually.