Associate Scientist - LNP Formulation & Development

Sanofi EU; Waltham (MA); On-site; USD 70,000 - 110,000; Full time

Job summary

Sanofi in Waltham, MA is seeking an Associate Scientist to support the Drug Product Platform and Early Clinical Development Team. This role emphasizes formulation and/or process development with growing laboratory skills in LNP formulation.

You will work with senior scientists to transfer and accelerate new LNP formulations into CMC development and contribute to developability packages, helping establish initial formulation processes for new LNPs.

Qualifications

• Bachelor's degree in a related scientific discipline.
• Minimum of 2 years of formulation, process development, or laboratory research.
• Preferred: Master's degree in a relevant scientific discipline.
• Experience with LNP production or analytical characterization techniques.
• Experience with electronic lab notebooks.

Responsibilities

• Support the formulation optimization and/or process understanding of mRNA-containing lipid nanoparticle (LNP) formulation and production processes under guidance from senior scientists.
• Assist the Research team in transferring and accelerating new LNP composition formulations into CMC development.
• Conduct small-scale multi-component LNP formulating experiments to support the developability assessment of new LNP formulations.
• Contribute to the compilation of Developability packages for new LNP formulations.
• Assist in developing initial formulation processes for new LNP formulations.
• Perform in-process drug product characterization under supervision.
• Perform routine and some complex analytical methods to characterize new formulations and support troubleshooting as needed.
• Support coordination with the Analytical Sciences department on LNP characterization analysis.

Skills

Laboratory skills

Formulation expertise

Process development

LNP knowledge

Analytical methods

Education

Bachelor's degree in Pharmaceutical Sciences, Chemistry, Chemical Engineering, Biomedical Engineering, or a related scientific discipline

Master's degree in a relevant scientific discipline

Tools

Electronic lab notebook systems

Job description

Sanofi in Waltham, MA is seeking an Associate Scientist to support the Drug Product Platform and Early Clinical Development Team. This role emphasizes formulation and/or process development with growing laboratory skills in LNP formulation.

You will work with senior scientists to transfer and accelerate new LNP formulations into CMC development and contribute to developability packages, helping establish initial formulation processes for new LNPs.