Associate Director, Quantitative PK/PD & Pharmacometrics

Merck & Co.; Elmora (NJ); Hybrid; USD 157,000 - 247,000; Full time

Benefits offered by this job

Medical, dental, vision insurance

401(k) retirement benefits

Paid holidays and vacation

Job summary

Merck & Co., Inc. is seeking an Associate Director in Rahway, NJ, and West Point, PA to lead quantitative pharmacology and pharmacometrics efforts across cardiometabolic programs.

You will design model-based strategies, run translational simulations, and influence decision-making in development and discovery. You will work with cross-functional teams, including external partners, to deliver mechanistic and population PK/PD analyses.

Qualifications

• Ph.D. or equivalent degree with at least 4 years of relevant experience; PharmD or equivalent degree with at least 6 years of relevant experience; or MS with at least 8 years of relevant experience.
• Educational background in biopharmaceutics, pharmaceutical sciences, pharmacometrics, chemical or biomedical engineering, or related quantitative discipline.
• Experience conducting population PK and PK/PD analyses using standard pharmacometrics software.
• Strong written and verbal communication skills with collaboration across disciplines.
• Knowledge in modeling complex therapeutics, mechanistic modeling/QSP.

Responsibilities

• Develop and apply model-based strategies including translational PK/PD, mechanistic models, population PK/PD analyses, and clinical trial simulations to inform quantitative decision-making across development programs.
• Represent QP2 on cardiometabolic discovery and development teams to support evidence-based advancement of programs.
• Partner with functional area colleagues, vendors, and strategic partners to build aligned model-informed approaches.
• Collaborate across disciplines on study design, protocol development, execution, data interpretation, and reporting.
• Maintain understanding of regulatory expectations and contribute to regulatory documents and submissions.
• Provide scientific input on modeling strategies and interpretation with pharmacometrics colleagues.

Skills

BI

Data Modeling

Data Science

Machine Learning

Database Design

Data Engineering

Data Visualization

Software Development

Stakeholder Management

Waterfall Model

Education

Ph.D. or equivalent

MS or equivalent

PharmD or equivalent

Tools

R

Matlab

Phoenix

NONMEM

Monolix

Job description

Merck & Co., Inc. is seeking an Associate Director in Rahway, NJ, and West Point, PA to lead quantitative pharmacology and pharmacometrics efforts across cardiometabolic programs.

You will design model-based strategies, run translational simulations, and influence decision-making in development and discovery. You will work with cross-functional teams, including external partners, to deliver mechanistic and population PK/PD analyses.