Associate Director, Quantitative Pharmacology & Pharmacometrics - Mechanistic Modeling, Immunology

Scorpion Therapeutics; Pennsylvania; Hybrid; USD 180,000 - 230,000; Full time

Job summary

Scorpion Therapeutics seeks an Associate Director specializing in mechanistic modeling and quantitative drug development within immunology. You will support translational research and clinical programs, designing model analysis plans across PK/PD, PBPK, and QSP.

The role involves collaborating with cross-functional teams and external vendors, developing translational strategies, and performing clinical trial simulations to inform dose and schedule decisions for immunologic therapeutics.

Qualifications

• PhD (≥4 yrs), PharmD (≥6 yrs), or MS (≥8 yrs) with extensive experience in pharmacometrics/biopharmaceutics or related fields.
• Proficiency in modeling software: Phoenix, R, NONMEM, Monolix, Matlab.
• Strong communication skills.

Responsibilities

• Independently design and execute model analysis plans using PK/PD, PBPK, QSP, and other mechanistic models.
• Collaborate with cross-functional teams and external vendors.
• Develop translational strategies, perform clinical trial simulations, and inform dose/schedule decisions to advance immunologic therapeutics.

Skills

Pharmacometrics

Cross-functional

Education

PhD/PharmD/MS

Tools

Phoenix

R

NONMEM

Monolix

Matlab

Job description

Role

Associate Director specializing in mechanistic modeling and quantitative drug development within immunology, supporting translational research and clinical programs.

Responsibilities

• independently design and execute model analysis plans using PK/PD, PBPK, QSP, and other mechanistic models
• collaborate with cross-functional teams and external vendors
• develop translational strategies, perform clinical trial simulations, and inform dose/schedule decisions to advance immunologic therapeutics

Qualifications

• Ph.D. (≥4 yrs), PharmD (≥6 yrs), or MS (≥8 yrs) with extensive experience in pharmacometrics, biopharmaceutics, or related fields
• proficiency in modeling software (Phoenix, R, NONMEM, Monolix, Matlab)
• strong communication skills

Preferred

• a proven record of impactful model-based drug development, immunology knowledge, experience with biologics, and integrating AI/ML into modeling workflows

High-value biopharma specifics

• focus on immunologic disorders, biologics or complex therapeutics, and the application of mechanistic and predictive modeling to inform clinical development decisions

Work setup

hybrid, with a 10% travel requirement.