Lead Mechanistic Modeling for Immunology Drug Development

MSD; Rahway (NJ); Hybrid; GBP 119,000 - 187,000; Full time

Benefits offered by this job

Medical insurance

Dental and Vision

401(k)

Hybrid work model

Job summary

Merck & Co., Inc. seeks an Associate Director to lead mechanistic modeling for immunology translational work. You will independently design analyses, integrate preclinical and clinical data, and influence dose selection with PK/PD/QSP models.

You will join cross-functional teams, apply quantitative skills, and communicate findings clearly to stakeholders while mentoring colleagues and partnering with vendors.

Qualifications

• Hands-on population PK/PKPD/QSP modeling with standard tools.
• Educational background in biopharmaceutics or pharmacometrics.
• Strong communication and cross-functional collaboration skills.

Responsibilities

• Design and execute model analysis plans informing translational questions.
• Develop PK/PD strategies and perform clinical trial simulations.
• Model-based dose selection and trial design recommendations.
• Collaborate across functions and external vendors to align strategies.

Skills

Data Analysis

Data Modeling

Data Visualization

Drug Development

Immunology Research

Machine Learning

Model Development

Pharmacology

Pharmacometrics

PKPD Modeling

Quantitative Models

Scientific Presentations

Education

Ph.D. or equivalent degree

PharmD or equivalent degree

MS or equivalent degree

Tools

Phoenix

R

Matlab

NONMEM

Monolix

Job description

Merck & Co., Inc. seeks an Associate Director to lead mechanistic modeling for immunology translational work. You will independently design analyses, integrate preclinical and clinical data, and influence dose selection with PK/PD/QSP models.

You will join cross-functional teams, apply quantitative skills, and communicate findings clearly to stakeholders while mentoring colleagues and partnering with vendors.