Analytical QC Scientist — Single Cell & Spatial Biology

10x Genomics Inc; Pleasanton (CA); On-site; USD 123,000 - 167,000; Full time

Job summary

10x Genomics Inc is seeking an Analytical Development Scientist to lead the development and implementation of QC assays for single cell and spatial biology products. You will design end-to-end QC strategies from materials to finished goods and optimize current methods while collaborating with R&D and Manufacturing teams globally.

The role requires deep analytical chemistry and molecular biology experience, strong documentation skills, and effective cross-functional communication to drive quality

Qualifications

• PhD or MS in Molecular Biology, Biochemistry, Organic Chemistry, Analytical Chemistry, or related fields.
• 2+ years (PhD) or 5+ years (MS) in biotechnology or analytical chemistry industrial experience.
• Experience designing, developing, and implementing QC strategies from raw materials to finished products.
• Hands-on experience with analytical chemistry and/or molecular biology techniques such as characterization and quantification of oligonucleotides, proteins, enzymes, antibodies, and small molecules.
• Development of HPLC methods for characterization of small molecules.
• Experience with PCR and qPCR for quantification.
• Demonstrated ability to document and transfer complex analytical assays into manufacturing and QC environments.
• Strong collaboration and communication skills across technical and non-technical teams.

Responsibilities

• Lead development, validation, and implementation of QC methods for single cell and spatial biology products.
• Design, document, and implement end-to-end QC strategies from materials to finished goods.
• Optimize and improve existing QC strategies and methods.
• Train QC teams domestically and internationally on analytical assays and compliance.
• Troubleshoot product formulation, storage, and QC issues.
• Design experiments to understand molecular interactions and root causes using DOE or similar methods.
• Document and update SOPs and present findings to cross-functional teams.

Skills

Mass spectrometry

LC/MS

qPCR

PCR

Molecular biology

Analytical chemistry

DOE (Design of Experiments)

SOP documentation

Cross-functional collaboration

Education

PhD in Molecular Biology

MS in Chemistry or related field

Tools

HPLC

Flow cytometry

Gel electrophoresis

JMP or R

Job description

10x Genomics Inc is seeking an Analytical Development Scientist to lead the development and implementation of QC assays for single cell and spatial biology products. You will design end-to-end QC strategies from materials to finished goods and optimize current methods while collaborating with R&D and Manufacturing teams globally.

The role requires deep analytical chemistry and molecular biology experience, strong documentation skills, and effective cross-functional communication to drive quality