AI-Enabled Principal Full-Stack Engineer

eClinical Solutions LLC; Mansfield, Northern (MA, KY); Hybrid; USD 152,000 - 190,000; Full time

Job summary

eClinical Solutions is seeking a Principal Full Stack Software Engineer to lead the elluminate Product Development team. You will design and build core services and user experiences for a next-generation clinical data and analytics platform, influencing architecture, standards, and technical direction.

The role emphasizes hands-on development, mentoring, and delivering AI-assisted workflows into production-grade systems while aligning with enterprise regulations and quality standards.

Qualifications

• Bachelor’s or Master’s degree in Computer Science or equivalent practical experience.
• 10+ years in software design and development using the Microsoft technology stack preferred.
• Expert-level proficiency in C#, .NET, and ASP.NET (MVC/Web APIs).
• Strong experience building full-stack web applications (Angular, TypeScript, HTML, CSS).
• Solid understanding of software design principles, patterns, and best practices.
• Experience across the full Software Development Lifecycle (Agile preferred).
• Proven ability to work independently while collaborating effectively in a fast-paced environment.
• Excellent communication, documentation, and technical leadership skills.

Responsibilities

• Design, develop, test, and deploy scalable, secure, and highly interactive web applications.
• Own and evolve core platform modules, from concept through release and support.
• Influence application and system architecture with a focus on performance, reliability, security, and maintainability.
• Lead by example through clean, well-tested code, thoughtful design reviews, and pragmatic technical decisions.
• Collaborate closely with Product Management, QA, and other engineers throughout the SDLC.
• Provide technical mentorship and guidance to other engineers on the team.
• Diagnoses and resolves complex production issues across distributed systems.
• Ensure solutions meet eClinical Solutions quality standards and applicable industry regulations.
• Contribute to technical documentation including design specs, acceptance criteria, and release notes.

Skills

C#

.NET

ASP.NET

Full-stack web apps

Angular

TypeScript

HTML

CSS

Agile

Leadership

Education

Bachelor’s or Master’s degree in Computer Science or equivalent

Tools

Angular

TypeScript

HTML

CSS

Microsoft SQL Server

AWS

Job description

eClinical Solutions is seeking a Principal Full Stack Software Engineer to lead the elluminate Product Development team. You will design and build core services and user experiences for a next-generation clinical data and analytics platform, influencing architecture, standards, and technical direction.

The role emphasizes hands-on development, mentoring, and delivering AI-assisted workflows into production-grade systems while aligning with enterprise regulations and quality standards.