Principal Full-Stack Engineer — AI-Driven Health Cloud

eClinical Solutions, LLC; Chelmsford (MA); On-site; USD 152,000 - 190,000; Full time

Job summary

eClinical Solutions is transforming clinical development with elluminate, our Clinical Data Cloud, helping life sciences unify, analyze, and unlock data value faster.

As a Principal Full Stack Software Engineer, you will be a technical leader within the elluminate Product Development team, helping design and build core services and user experiences of a next-generation clinical data and analytics platform—while influencing architecture, engineering standards, and technical direction.

Qualifications

• Bachelor’s or Master’s degree in Computer Science or equivalent practical experience.
• 10+ years in software design and development using the Microsoft technology stack preferred.
• Expert-level proficiency in C#, .NET, and ASP.NET (MVC/Web APIs).
• Strong experience building full‑stack web applications (Angular, TypeScript, HTML, CSS).
• Solid understanding of software design principles, patterns, and best practices.
• Experience across the full Software Development Lifecycle (Agile preferred).
• Proven ability to work independently while collaborating effectively in a fast‑paced environment.
• Excellent communication, documentation, and technical leadership skills.

Responsibilities

• Design, develop, test, and deploy scalable, secure, and highly interactive web applications.
• Own and evolve core platform modules, from concept through release and support.
• Influence application and system architecture with a focus on performance, reliability, security, and maintainability.
• Lead by example through clean, well‑tested code, design reviews, and pragmatic technical decisions.
• Collaborate closely with Product Management, QA, and other engineers throughout the SDLC.
• Provide technical mentorship and guidance to other engineers on the team.
• Diagnoses and resolves complex production issues across distributed systems.
• Ensure solutions meet eClinical Solutions quality standards and applicable industry regulations.

Skills

Leadership

Mentoring

Communication

Independent work

Technical leadership

Education

Bachelor’s or Master’s degree in Computer Science

equivalent practical experience

Tools

C#

.NET

ASP.NET (MVC/Web APIs)

Angular

TypeScript

HTML/CSS

Python

SQL Server

Azure/OpenAI integration

Job description

eClinical Solutions is transforming clinical development with elluminate, our Clinical Data Cloud, helping life sciences unify, analyze, and unlock data value faster.

As a Principal Full Stack Software Engineer, you will be a technical leader within the elluminate Product Development team, helping design and build core services and user experiences of a next-generation clinical data and analytics platform—while influencing architecture, engineering standards, and technical direction.