Research Officer / Assistant (Analytical Development)

ESCO ASTER PTE. LTD.; Singapore; On-site; SGD 55,000 - 90,000; Full time

Job summary

Esco Aster Pte Ltd is hiring for an Analytical Development role based at our Singapore facility. The successful candidate will perform routine analytical testing, execute assays, and contribute to method development to support drug substance and product characterization.

Join a growing CDMO team, with opportunities to collaborate with Process Development and Quality, and to participate in technology transfer within a dynamic startup-phase environment.

Qualifications

• Hands-on experience with basic cell culture, cell-based assays and ELISA.
• Experience with analytical techniques such as HPLC, UV-Vis spectrophotometry and Karl Fischer titration.
• Experience in flow cytometry, qPCR and Western blotting would be an advantage with on-the-job training.
• Understand and work according to GDP and cGxP requirements.
• Meticulous in scheduling experiments and documenting analytical reports.
• Ability to communicate results with internal stakeholders and plan next steps.
• Willingness to learn new analytical techniques and deepen skills.
• Collaborate with cross-functional teams for tech transfer of analytics to operations.
• Perform tasks per regulations and site safety requirements.
• Undertake other tasks as assigned.

Responsibilities

• Perform routine analytical testing and assay execution.
• Develop and transfer analytical methods.
• Collaborate with Process Development and Quality teams on programs.
• Support investigations and project deliverables.

Skills

Cell culture

Cell-based assays

ELISA

HPLC

UV-Vis spectrophotometry

Karl Fischer titration

Flow cytometry

qPCR

Western blot

Education

Bachelor's degree in Life Sciences

Tools

Microsoft Excel

JMP

Prism

Job description

The Opportunity

Esco Lifesciences Group is Singapore’s most globalized life sciences company, with annual revenues close to SGD 200M and global operations in over 42 locations and 26 direct countries across North America, Europe, Asia, Oceania.

Esco Aster Pte Ltd is an affiliate of Esco Lifesciences Group and was first incorporated in 2017.

Esco Aster is a contract research development and manufacturing organization founded and deeply rooted by scientists that enables fellow scientists to translate their bench work into commercially available products at affordable prices. Our scientific work is in emerging and frontier biology utilizing cells or cell derived products.

Our first commercial breakthrough success is Esco Aster is commercially first in the world to be certified for cultivated/cell-based meat to FSSC 22000 and by a competent food regulatory body.

We are expanding towards the cell and gene therapy space with first in the region to operate an end-to-end integrated process from cell line creation, cell culture process development, downstream process development and analytical development. These processes are supported with full cGMP Capabilities to produce Drug Substance and small-scale fill & finish for final Cell Therapy Product.

The work we do creates a remarkable and lasting impact on our world. We offer you an opportunity to be part of this exciting journey to own your career and firsthand exposure to new emerging modalities supporting translational sciences.

Join us as we redefine BioSolutions for One World and One Health for the current and future generations to come.

Esco Aster.

One World Biosolutions for One Health.

Who we’re looking for

Desired profile of candidate

The ideal candidate should have hands-on experience or demonstrated competency in basic cell culture, cell-based assays, and ELISA, and/or analytical techniques such as HPLC, UV-Vis spectrophotometry, and Karl Fischer titration.

Experience in flow cytometry, qPCR, and Western blotting would be an advantage but is not essential, as relevant training will be provided on the job, if needed.

The candidate should also:

• Understand and be willing to work in accordance with Good Documentation Practice (GDP) and cGxP requirements.
• Meticulous and organized in scheduling experimental assays, documentation of analytical test reports, and drafting protocols.
• Ability to communicate and explain experimental results effectively with internal stakeholders and identify logical next steps of the experiment.
• Demonstrates a positive and proactive attitude and towards guidance. Willingness to learn new analytical techniques and demonstrate interest to continuous deepen skill expertise.
• Demonstrate collaborative efforts with cross functional teams in support of the technology transfer of analytical to operational department, including transferring of SOP and analytical assay.
• Perform tasks in accordance with applicable regulations and site safety requirements.
• Undertake other tasks as assigned based on project needs.

The Scope

You will be part of Esco Aster’s Analytical Development team and contribute to the company’s CDMO mission and objectives. As a member of the Analytical Development team, you will perform analytical tests and assays to support the testing and characterization of drug substances and drug products. The primary responsibilities of the role will include routine analytical testing, assay execution, and analytical method development activities. The role will require close collaboration with Process Development scientists and Quality team to support development programs, analytical investigations, method transfer, and project deliverables.

Primary work location: Ayer Rajah Crescent, Singapore.

Report To

Selected candidate will report to Head of Scientific & Sales Operations, or others as assigned.

Other Requirements

• Minimally Bachelor's degree in Life Sciences or related disciplines.
• Fresh graduates with research internship experience in academia or industry are welcome to apply
• Proficient in various software that supports scientific analysis (e.g. Microsoft excel, JMP, Prism etc)
• Able to work independently, self-starter, self-motivated and task oriented.
• Strong team player, develop positive relationships with a strong set of interpersonal skills.
• During the start-up phase of the team/facility, be adaptable to dynamic workflow changes and shifting priorities.

Apply now by submitting a Cover Letter and CV to [e-mail].