Scientist (Process Development)

Esco Aster; Singapore; On-site; SGD 70,000 - 90,000; Full time

Benefits offered by this job

Learning and Development

Competitive Compensation

Overseas Travel Opportunities

Job summary

A leading life sciences company in Singapore seeks a molecular biologist to support their contract development and manufacturing operations. The successful candidate will design and execute laboratory experiments, optimize upstream processes for mammalian cell cultures, and take part in project management. Applicants should possess a Bachelor's degree in Biology or related fields, and have experience in GLP and GMP. Join us in making impactful advancements in biosolutions.

Qualifications

• 4-5 years related laboratory experience including mammalian cell culture and stem cells.
• Experience with Good Laboratory Practices (GLP) and Good Manufacturing Practices (GMP) will be an advantage.
• Experience in isolation of stem cells, tissue banking and generation of cell bank.

Responsibilities

• Design and execute experiments to support client upstream processes.
• Evaluate and optimize existing client processes.
• Conduct scale-up experiments in larger bioreactors.
• Write client proposals and summarize project work.

Skills

Ability to read, analyze and interpret scientific data and publications

Excellent communication (oral and written)

Strong team player with interpersonal skills

Proficient in MS Office Suite

Education

Bachelor’s degree in Biology or related science

Tools

Bioreactor systems

ELISA

FACS

Job description

Join us for the world we are making, redefining biosolutions for current and future generations to come, transcending planetary boundaries, sustainability, and One Health.

Growth

Weempower each other to produce better resultsby providingprofessional advancement and personalgrowth.

Weare driven by the challenge of creating something new and discovering better opportunities.

We value a positive attitude. We make working a more pleasant experience for everyone.

Communication

We value communication, for it creates better intercultural relationships.

Competence

We focus onthings that matter mostand help each otherdrive success.

Commitment

We see the good. We work hard. We keep things in balance.

Growth

Weempower each other to produce better resultsby providingprofessional advancement and personalgrowth.

Weare driven by the challenge of creating something new and discovering better opportunities.

We value a positive attitude. We make working a more pleasant experience for everyone.

Communication

We value communication, for it creates better intercultural relationships.

Competence

We focus onthings that matter mostand help each otherdrive success.

We want ourworkforceto become a happier,
healthier, more productive place to work.

BENEFITS

Learning and
Development

Competitive
Compensation

Overseas
Travel Opportunities for
many positions

One Team, One Mission

Are you a seasoned professional looking
foryournext challenge? Be one of us!

The Opportunity

Esco Lifesciences Group is Singapore’s most globalizedlife sciences company, with annual revenues close to SGD 200M and globaloperations in over 42 locations and 26 direct countries across North America,Europe, Asia, Oceania.

Esco Aster Pte Ltd is an affiliate of EscoLifesciences Group and was first incorporated in 2017.

Esco Aster is a contract research development andmanufacturing organization founded and deeply rooted by scientists enablingfellow scientists to translate their bench work into commercially availableproducts at affordable prices.

Ourscientific work is in emerging and frontier biology utilizing cells as a finalproduct or deriving products from cells which often we use cells as the factoryto derive our target product.

Ourfirst commercial breakthrough success is Esco Aster is commercially first inclass being first in the world to be certified for cultivated/cell-based meatto FSSC 22000 and by a competent food regulatory body.

Weare first in the region to operate an end-to-end integrated full cell linecreation/immortalization or engineered cell line, cell culture processdevelopment, analytical development for stem cells and exosomes with full cGMPCapabilities from Drug Substance and small-scale fill & finish for finalCell Therapy Product.

The work we do creates a remarkable and lasting impacton our world. We offer you an opportunity to be part of this exciting journeyto own your career and firsthand exposure to new emerging modalities supportingtranslational sciences.

Join us as we redefine BioSolutions for One World andOne Health for the current and future generations to come.

One World Biosolutions for One Health.

Who we’re looking for

• Ability to read, analyze and interpret scientific data and publications
• Ability to author or review protocols, technical reports and technology transfer documents.
• Ability to author or review standard operating procedures and other related documents.
• Ability to define problems, collect data, establish facts, and draw conclusions.
• Ability to focus
• Repetitive motions due to certain laboratory techniques

Report To:

Selected candidate will report to CEO and others as assigned.

One World Biosolutions for One Health .

The Scope

You will be part of Esco Aster’s scientific division and contribute to the company’s CDMO mission and objectives. You will perform research and process development activities, mainly in support of mammalian cells production, in collaboration with internal and external stakeholders, clients and partners.

Job Responsibilities

Design and Independently Execute Experiments:

• Design and laboratory-scale experiments to support client upstream processes and requests.
• Perform assay development and data analysis.

Upstream Process Evaluation and Optimization:

• Evaluate and optimize existing client processes in preparation for scale-up.
• Propose improvements and modifications to enhance process efficiency.

Scale-up and Technology Transfer:

• Conduct scale-up experiments in larger bioreactors.
• Adapt processes to align with available on-site equipment.
• Facilitate technology transfer from clients, aiming at scaling up processes or implementing new technologies (e.g., perfusion, serum replacements).

Continuous Process Improvement:

• Proactively identify opportunities for process improvements.
• Initiate and drive enhancements to streamline processes.

Project Management and Documentation:

• Write client proposals, outlining milestones, timelines, and budgets for scale-up projects.
• Take ownership and accountability for all deliverables and milestones in assigned projects.
• Summarize project work in a formal report and communicate effectively to stakeholders.

Cross-Functional Collaboration:

• Collaborate across different teams to troubleshoot, test, and optimize various issues.
• Work seamlessly in a cross-functional environment.

Subject Matter Expert Support:

• Support sales, business development, product specialists, and associated departments as a subject matter expert.

Ad Hoc Tasks:

• Undertake other tasks as assigned based on project needs.

Flexible Work Schedules:

• Adapt work schedules as needed to accommodate cell culture schedules.

Requirements

• Bachelor’s degree in Biology or related science.
• At least 4-5 years related laboratory experience including mammalian cell culture and stem cells.
• Experience with Good Laboratory Practices (GLP) and Good Manufacturing Practices (GMP) will be an advantage.
• Proficient in MS Office Suite (Microsoft Word, PowerPoint, Excel).
• Experience in isolation of stem cells, tissue banking and generation of cell bank.
• Experience with cell assays such as FACS, ELISA, biological assays.
• Experience with bioreactor systems.
• General laboratory skills, good pipetting skills and experience with automation.
• Strong computer, scientific, and organizational skills.
• Excellent communication (oral and written) and attention to detail.
• Strong team player, develop positive relationship with a strong set of interpersonal skills.
• Ability to work independently and as part of a team, self-motivated, adaptable, and has a positive attitude.
• Ability to learn new techniques, perform multiple tasks simultaneously, keep accurate records, follow instructions, and comply with company policies.