Lead Scientist (Cell Line Creation)

Esco Aster; Singapore; On-site; SGD 50,000 - 70,000; Full time

Benefits offered by this job

Competitive compensation

Learning and development opportunities

Overseas travel opportunities

Job summary

A leading biotechnology firm in Singapore is seeking a Cell Line Development Scientist to join its team at Esco Aster Pte Ltd. The ideal candidate should have a Master's degree in Biology or related science and 1-2 years of laboratory experience, especially in mammalian cell culture and aseptic techniques. This role includes performing essential laboratory procedures, documenting results, and collaborating with internal and external partners. Strong communication skills and proficiency in Excel are required.

Qualifications

• 1-2 years related laboratory experience in mammalian cell culture.
• Microbiology/Cell biology background essential.
• Strong organizational skills with attention to detail.

Responsibilities

• Perform cell line development activities including cloning and analysis.
• Document and maintain accurate records as per GMP standards.
• Communicate effectively with clients and project stakeholders.

Skills

Aseptic techniques

Mammalian cell culture

Troubleshooting cell lines

Laboratory skills

Excel proficiency

Strong communication

Education

Masters in Biology or related science

Tools

Bioreactor systems

Job description

Join us for the world we are making, redefining biosolutions for current and future generations to come, transcending planetary boundaries, sustainability, and One Health.

Growth

Weempower each other to produce better resultsby providingprofessional advancement and personalgrowth.

Weare driven by the challenge of creating something new and discovering better opportunities.

We value a positive attitude. We make working a more pleasant experience for everyone.

Communication

We value communication, for it creates better intercultural relationships.

Competence

We focus onthings that matter mostand help each otherdrive success.

Commitment

We see the good. We work hard. We keep things in balance.

Growth

Weempower each other to produce better resultsby providingprofessional advancement and personalgrowth.

Weare driven by the challenge of creating something new and discovering better opportunities.

We value a positive attitude. We make working a more pleasant experience for everyone.

Communication

We value communication, for it creates better intercultural relationships.

Competence

We focus onthings that matter mostand help each otherdrive success.

We want ourworkforceto become a happier,
healthier, more productive place to work.

BENEFITS

Learning and
Development

Competitive
Compensation

Overseas
Travel Opportunities for
many positions

One Team, One Mission

Are you a seasoned professional looking
foryournext challenge? Be one of us!

The Opportunity

Esco Lifesciences Group is Singapore’s most globalized life sciences company, with annual revenues close to SGD 200M and global operations in over 42 locations and 26 direct countries across North America, Europe, Asia, Oceania.

Esco Aster Pte Ltd is an affiliate of Esco Lifesciences Group and was first incorporated in 2017.

Esco Aster is a contract research development and manufacturing organization founded and deeply rooted by scientists enabling fellow scientists to translate their bench work into commercially available products at affordable prices.

Our scientific work is in emerging and frontier biology utilizing cells as a final product or deriving products from cells which often we use cells as the factory to derive our target product.

Our first commercial breakthrough success is Esco Aster is commercially first in class being first in the world to be certified for cultivated/cell-based meat to FSSC 22000 and by a competent food regulatory body.

We are first in the region to operate an end-to-end integrated full cell line creation/immortalization or engineered cell line, cell culture process development, analytical development for stem cells and exosomes with full cGMP Capabilities from Drug Substance and small-scale fill & finish for final Cell Therapy Product.

The work we do creates a remarkable and lasting impact on our world. We offer you an opportunity to be part of this exciting journey to own your career and firsthand exposure to new emerging modalities supporting translational sciences.

Join us as we redefine BioSolutions for One World and One Health for the current and future generations to come.

One World Biosolutions for One Health.

Who we’re looking for

• Ability to read, analyze and interpret scientific data and publications
• Ability to author or review protocols, technical reports and technology transfer documents.
• Ability to author or review standard operating procedures and other related documents.
• Ability to define problems, collect data, establish facts, and draw conclusions.
• Ability to focus
• Repetitive motions due to certain laboratory techniques

The Scope

You will be part of Esco Aster’s Cell Line Creationdivision and contribute to the company’s CDMO mission and objectives. You willplan and execute experiments in support of the cell line generation divisionand generate high productivity mammalian cell lines and execute the diversecell culture experiments required to produce various vaccine candidates andantibodies, in collaboration with internal and external stakeholders, clientsand partners.

Primary work location: Ayer Rajah, Singapore

Reports to: Head of Scientific & SalesOperations

Job Responsibilities

• Perform key activities associated withcell line development including molecular cloning, in vitro transcription,transfection, Single cell cloning, clone selection, characterization andcell banking.
• Perform tasks in a compliant manneraccording to SOP guidelines and regulations.
• Write technical reports and campaignsummaries.
• Prepare solutions and culture media(small scale as well as large scale).
• Perform analysis of cell metabolites,medium components etc. by Bioanalysis.
• Maintain accurate batch records andresults following good manufacturing practices (GMP).
• Work independently and efficiently.
• Document work clearly and perform tests accurately.
• Communicate effectively with client staffmembers and provide updates on the progress of the project.
• Liaise with vendors and third-partytesting labs to procure materials obtain test results in a timely manner.

Requirements

• At least 1-2 years related laboratoryexperience including aseptic and mammalian cell culture techniques.
• Microbiology/Cell biology Background.
• Experience with bioreactor systems.
• Good trouble shootingability with cell lines.
• General laboratory skills,good pipetting skills and experience with automation.
• Experience using formulasand linking spreadsheets in Excel.
• Strong computer, scientific,and organizational skills.
• Excellent communication(oral and written) and attention to detail.
• Ability to work independentlyand as part of a team, self-motivation, adaptability, and a positive attitude.
• Ability to learn newtechniques, perform multiple tasks simultaneously, keep accurate records,follow instructions, and comply with company policies.
• A friendly and pleasantdisposition
• Masters in Biology or relatedscience and 1-2 Years Mammalian Cell Culture experience.