MS&T Engineer-Upstream-BioPharma

EFOR (formerly Process Engineering Specialists); Singapore; On-site; SGD 90,000 - 140,000; Full time

Job summary

PES is an international services company serving the Life Sciences industry with a Singapore site focusing on upstream MSAT engineering for NPI and tech transfer. The role provides scientific leadership on complex investigations and cross-network alignment within the PD team.

The Upstream MSAT Engineer applies strong biologics process knowledge to assess performance, drive risk-based recommendations, and support readiness for manufacturing campaigns and PPQ.

Qualifications

Responsibilities

• Lead NPI and technology transfer workstreams; document risks and knowledge transfer.
• Translate process characterization and scale-up knowledge into site requirements; support readiness for engineering runs and PPQ.
• Identify gaps/risks; propose mitigations; escalate decisions to Tech Transfer Lead and PD leadership.
• Provide support for cell culture, harvest, and purification processes.
• Evaluate manufacturing performance and complex process issues using knowledge and experience.
• Collaborate with Manufacturing, Quality and others to resolve process challenges.
• Lead senior guidance on deviation investigations: hypotheses, data, root cause, impact.
• Integrate data to reach conclusions and risk-based recommendations.
• Coach PD engineers in problem solving and communication to leadership.

Job description

PES is an international services company providing Project Management, Construction Management, Commissioning & Qualification and Automation services to our clients in the pharmaceutical, nutritional and related sectors.

With offices across Europe, Asia and US, our core focus is on consistently delivering high quality outcomes for our multinational clients.

This focus, and our people's experience in delivering consistent quality results for our clients over the past 20 years has been key to our success to date.

We are currently looking for MS&T Engineer-Upstream to join us on a permanent basis to help us deliver various projects in the Life Sciences Industry.

Position Overview

The Upstream MSAT Engineer provides experienced scientific and process engineering support for new product introduction (NPI), technology transfer and commercial biologics manufacturing at a Singapore manufacturing site. The role independently executes assigned NPI and technology transfer workstreams, while giving senior technical guidance to the commercial Process Development team on complex investigations, process troubleshooting, campaign readiness, cross-network technical alignment and continuous improvement. The successful candidate will apply strong biologics process knowledge, manufacturing experience and scientific judgment to assess process performance, identify technical risks and develop evidence-based recommendations. The position operates within the established governance structure and is not the formal Technology Transfer Lead, but provides technical leadership for assigned workstreams and escalates key decisions through the Technology Transfer Lead and Process Development leadership.

Key Responsibilities

• Independently lead assigned NPI and technology transfer technical workstreams, including process knowledge transfer, facility and process fit assessment, technical documentation and risk identification
• Translate process characterization, scale-up and manufacturing knowledge into site requirements, and support readiness for engineering runs and PPQ
• Identify technical gaps and risks, develop recommendations and mitigation options, and escalates key decisions through the Technology Transfer Lead and PD leadership
• Provide scientific and engineering support to the commercial PD team for cell culture, harvest and/or purification processes
• Evaluate manufacturing performance and complex process issues using process knowledge, historical experience and engineering principles
• Partner with Manufacturing, Quality and other technical functions to resolve process challenges and support reliable commercial manufacturing
• Lead or provide senior guidance on complex deviation investigations, including hypothesis development, data assessment, root cause evaluation and technical impact assessment
• Integrate process, equipment, manufacturing and historical data to reach scientifically justified conclusions and risk-based recommendations
• Coach PD engineers in structured problem solving, investigation strategy and clear technical communication to Manufacturing, Quality and leadership

PES International operates as an equal opportunity employer. No terminology in this advert is intended to discriminate on the grounds of age, race, religion, sexual orientation or any other factors with no bearing to employment skills and we confirm that we are happy to accept applications from persons of any background for this role.