Lead Synthetic Chemist, Oligonucleotide Therapeutics

AstraZeneca; Sweden; On-site; SEK 700,000 - 950,000; Full time

Job summary

AstraZeneca in Gothenburg seeks a Synthetic Chemist to advance oligonucleotide therapeutics. You will design and execute synthetic routes for nucleotide compounds and conjugates, focusing on innovative approaches and rigorous purification/characterization.

Applicants should hold a PhD in Organic Chemistry with hands-on experience in oligonucleotide synthesis, and excel at collaborative, multidisciplinary research within Discovery Sciences. English proficiency and a teamwork mindset are essential.

Qualifications

• PhD in Organic Chemistry with emphasis on synthetic methodologies.
• Experience in oligonucleotide or peptide synthesis is required.
• Ability to design and execute experiments independently.

Responsibilities

• Develop oligonucleotide drugs and related conjugates to support AstraZeneca's pipeline.
• Synthesize and purify nucleotide compounds and characterize products.
• Collaborate across Discovery Sciences to advance oligonucleotide therapeutics.
• Contribute to publication track record through high-quality research.

Skills

Advanced synthetic chemistry

Oligonucleotide synthesis

Autonomous experimental design

Team collaboration

Education

PhD in Organic Chemistry

Job description

AstraZeneca in Gothenburg seeks a Synthetic Chemist to advance oligonucleotide therapeutics. You will design and execute synthetic routes for nucleotide compounds and conjugates, focusing on innovative approaches and rigorous purification/characterization.

Applicants should hold a PhD in Organic Chemistry with hands-on experience in oligonucleotide synthesis, and excel at collaborative, multidisciplinary research within Discovery Sciences. English proficiency and a teamwork mindset are essential.