Senior Synthetic Chemist — Oligonucleotide Therapeutics

AstraZeneca GmbH; Mölndals kommun; On-site; SEK 700,000 - 900,000; Full time

Job summary

AstraZeneca in Gothenburg, Sweden seeks a Synthetic Chemist to drive oligonucleotide drug development within the Discovery Sciences division. You will lead synthesis efforts, purify and characterize compounds, and collaborate with multi‑disciplinary teams to advance the pipeline.

The role emphasizes rigorous synthetic techniques, data analysis, and contributing to publications while working in a dynamic, inclusive environment.

Qualifications

• PhD in Organic Chemistry is required and ongoing scientific excellence is expected.
• Experience in oligonucleotide or peptide synthesis is highly desirable.
• Ability to design and execute experiments autonomously.
• Knowledge of oligonucleotide therapeutics, design and data analysis is a plus.

Responsibilities

• Develop oligonucleotide drugs to support AstraZeneca's pipeline using cutting‑edge technologies.
• Synthesize nucleotide/oligonucleotide compounds and conjugated oligonucleotide therapeutics; purify and characterize products.
• Collaborate across AstraZeneca functions for biological evaluation and high‑impact publication output.

Skills

Synthesis design

Purification & characterization

Autonomous experiment design

Oligonucleotide chemistry know‑how

Education

PhD in Organic Chemistry

Post‑doc experience

Job description

AstraZeneca in Gothenburg, Sweden seeks a Synthetic Chemist to drive oligonucleotide drug development within the Discovery Sciences division. You will lead synthesis efforts, purify and characterize compounds, and collaborate with multi‑disciplinary teams to advance the pipeline.

The role emphasizes rigorous synthetic techniques, data analysis, and contributing to publications while working in a dynamic, inclusive environment.