Research Fellow: Brain Tumor Immunology & PDE Models

Fundação GIMM

Portugal

On-site

EUR 12,000 - 13,000

Full time

9 days ago

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Job summary

Fundação GIMM invites applications for a research fellowship in the Luís Graça Lab to work on immunology, cancer and neuro-oncology projects. The role covers maintaining cell cultures, establishing PDE models and biobanks, and evaluating interactions between PBMCs and PDE, alongside assessing T-cell activation against brain tumor cells in vitro.

The fellowship starts December 2026 for four months, with possible renewal per project rules, and will be supported by a monthly stipend and social

Qualifications

  • BSc degree in Biology, Biomedical Sciences, Life Sciences or a related field (mandatory).
  • Excellent written and spoken English (mandatory).
  • Experience in cell culture, human tissue processing and in vitro experimental models (mandatory).
  • Experience in the establishment of patient-derived explants (PDE) (mandatory).
  • Experience in PBMC isolation (mandatory).
  • Experience in spectral flow cytometry, including panel design with more than 15 colours, sample processing and data analysis (mandatory).

Responsibilities

  • Maintenance of cell cultures.
  • Establishment of glioblastoma PDE model.
  • Characterization of PDE in culture over weeks.
  • Establishment of a PDE biobank.
  • Evaluation of co-culture of PBMCs and PDE.
  • Assessment of T-cell activation and cytotoxic activity against brain tumor cells in vitro.

Skills

Excellent English (mandatory)
Cell culture
PDE establishment
PBMC isolation
Spectral flow cytometry
Molecular biology
Confocal microscopy (valuable)

Education

Bachelor Degree or equivalent

Tools

FlowJo
Fiji
GraphPad Prism
R/RStudio

Job description

Fundação GIMM invites applications for a research fellowship in the Luís Graça Lab to work on immunology, cancer and neuro-oncology projects. The role covers maintaining cell cultures, establishing PDE models and biobanks, and evaluating interactions between PBMCs and PDE, alongside assessing T-cell activation against brain tumor cells in vitro.

The fellowship starts December 2026 for four months, with possible renewal per project rules, and will be supported by a monthly stipend and social

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