1 (one) Research Fellowship (BI) for Master enrolled in non-degree course #5420

FCiências.ID; Portugal; On-site; EUR 14,000 - 17,000; Full time

Benefits offered by this job

Seguro de acidentes pessoais

Segurança social voluntária

Job summary

FCiências.ID procura uma Bolsista de Investigação para a BioISI - Instituto de Ciências da Biossistemas e Integrativas da Universidade de Lisboa. O estágio é de 6 meses, com início em janeiro de 2027, podendo prorrogar conforme regulamento da FCT, IP.

A posição envolve produção e caracterização de proteínas associadas a doenças, com apoio de supervisão do Prof. Cláudio M. Gomes. Enquadramento em um projeto de alto nível científico no BioISI.

Qualifications

• Mestrado concluído.
• Experiência em expressão e purificação de proteínas recombinantes, incluindo proteína intrinsecamente desordenada amyloide-beta.
• Experiência com chaperonas moleculares e caracterização biofísica/química de proteínas, incluindo estudos de agregação de proteínas.

Responsibilities

• Produção e análise biofísica de proteínas intrinsecamente desordenadas associadas à doença e de chaperonas moleculares para ensaios de agregação/phase separation.
• Caracterização experimental de separação de fases proteica e agregação usando ensaios cinéticos fluorescenciais e métodos biofísicos para dados quantitativos.
• Análise computacional de interações proteína–proteína e simulações de interações envolvendo chaperonas.
• Participação em atividades de demonstração, divulgação e disseminação.

Skills

Protein expression

Protein purification

Molecular chaperones

Protein characterization

Education

Master's degree completed

Tools

Circular dichroism

Fluorescence spectroscopy

Job description

Organisation/Company FCiências.ID Department Bolsas Research Field Chemistry » Biochemistry Biological sciences Researcher Profile First Stage Researcher (R1) Positions Master Positions Application Deadline 27 Nov 2026 - 23:59 (Europe/Lisbon) Country Portugal Type of Contract Not Applicable Job Status Not Applicable Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Reference Number 2024.15005.PEX Is the Job related to staff position within a Research Infrastructure? No

Offer Description

1 (one) Research Fellowship (BI) for Master enrolled in non-degree course

• Scientific Area: Biochemistry; Biological Sciences
  
• Admission requirements: a) A master’s degree completed;
  b) Demonstrated experience in recombinant protein expression and purification, including the intrinsically disordered protein amyloid-beta – information provided in the CV and/or motivation letter;
  c) Experience with molecular chaperones and in the biochemical and biophysical characterisation of proteins, including protein aggregation studies – information provided in the CV and/or motivation letter.
  
• Additional optional skills and qualifications: a) Laboratory R&D activities, including bacterial culture, recombinant protein expression and purification using medium- or high-pressure chromatography systems, and biochemical characterisation – information provided in the CV and/or motivation letter;
  b) Relevant scientific and/or professional training in biochemical and biophysical methods for protein characterisation – information provided in the CV and/or motivation letter;
  c) Experience with techniques for the structural characterisation of proteins, such as circular dichroism and fluorescence – information provided in the CV and/or motivation letter;
  d) Experience with kinetic methods for investigating protein aggregation based on microplate fluorescence measurements and the associated mechanistic analysis – information provided in the CV and/or motivation letter;
  e) Knowledge of the application of computational methods to investigate and model protein–protein interactions;
  f) Availability to travel abroad – information provided in the CV and/or motivation letter;
  g) Fluency in written and spoken English (upper-intermediate level, equivalent to level B2 or above of the Common European Framework of Reference for Languages, CEFR) – information provided in the CV and/or motivation letter.
  
• Contracting requirements: Presentation of the academic qualifications and/or diplomas, if applicable. Enrolment in a non‑degree course developed in association or cooperation between a High Education Institution and one or multiple research units.
  
• Work plan: a) Production and biophysical analysis of disease‑associated intrinsically disordered proteins and molecular chaperones for aggregation/phase separation assays;
  b) Experimental characterisation of protein phase separation and aggregation using fluorescence‑based kinetic assays and biophysical methods to obtain quantitative data on the effects of molecular chaperones and biological modulators; c) Computational analysis of protein–protein interactions and simulations of interactions involving molecular chaperones;
  d) Participation in demonstration, promotion and dissemination activities.
  
• Place of work: The work will be developed at theBioISI - Biosystems and Integrative Sciences Institute , Faculdade de Ciências da Universidade de Lisboa , under the scientific supervision of Professor Cláudio M. Gomes .
  
• Fellowship duration: This position is initially opened for 6 months due to start in January 2027 . The fellowship contract may be potentially renewed for until the end of the project, in accordance with the provisions of Regulation of Research Fellowships from the Foundation for Science and Technology, I.P.
• Monthly allowance: The fellowship amounts to 1359,64€, according to table values of the fellowships awarded directly by the FCT, IP.The fellowship holder will have a personal accident insurance and can ensure the right to social security through adherence to the voluntary social insurance scheme, if not covered by any other social protection scheme, pursuant to C ódigo dos Regimes Contributivos do Sistema Previdencial de Segurança Social. The fellowship will be paid monthly by bank transfer.
  
• Evaluation and selection process: Candidates will be assessed by ii) curriculum vitae (70%); ii) motivation letter (30%). If the jury considers it necessary, an interview may be conducted with the 3 (three) best candidates based on the sum of criteria i) and ii). If an interview takes place, the sum of the evaluations obtained in evaluation criteria i) and ii will correspond to 70% of the final classification, and the interview will correspond to 30%.
  Applicants whose application is scored with a final classification of less than 70 points are not eligible for granting a fellowship.
  
• Publication/notification of results: The results will be published on the FCiências.ID electronic recruitment platform ( https://concursus.ciencias.ulisboa.pt ), through the publication of the minutes of the Selection Committee meeting. Candidates will also be notified by email, using the email address provided in their application. Candidates who have not provided an email address will be notified exclusively through the electronic recruitment platform, where they can consult the minutes and find out the results .
  
• Deadlines: This call for applications is open from 16/11/2026 to 27/11/2026 .
  
• Application:Applications will be submitted online, through the electronic platform of FCiências.ID - https://concursus.ciencias.ulisboa.pt , by attaching the following documents:
  a) Curriculum vitae;
  b) Certificate of the academic degree required in the public notice Note 1, 2 ;
  c) Motivation letter;
  d) Other documents considered relevant.
  
• Processing of personal data: FCiências.ID – Associação para a Investigação e Desenvolvimento de Ciências, as the controller under the General Data Protection Regulation, collects and processes the personal data requested in the context indicated in paragraph 14., under the legitimate interests in ensuring the award of the research fellowship to candidates with the indicated profile.
  The personal data will be kept for the period necessary for the execution of the purposes for which they are intended, being ensured the processing and protection in an appropriate and diligent way, the confidentiality and integrity of these data, through appropriate technical and organizational measures.
  Personal data may be transmitted to third parties, namely the entity funding the research project, solely for the purposes specifically established. In this sense, whenever the transfer of personal data to countries outside the European Union and/or international organizations is necessary, compliance with the applicable legal provisions is ensured.
  You have the right to request access, rectification, elimination, limitation of processing, the right to object and also data portability (if technically feasible), through the e-mail address: [e-mail] . You also have the right to lodge a complaint with the National Data Protection Commission.
  For more information, we recommend consulting the Internal Rules of Data Protection of FCiências.ID - Association for Research and Development of Sciences at https://fciencias-id.pt/ .
  
• Time limits for the appeal procedure: Following the notification of the results, candidates have 10 business days to, should they wish to do so, submit their comments under the prior hearing procedure, in accordance with Articles 121 et seq. of the Código do Procedimento Administrativo (Portuguese Administrative Procedure Code). Comments must be submitted by email to [e-mail] . Once this period has elapsed and the comments received have been reviewed, the final decision will be published, and candidates will be notified through the same channels, in accordance with paragraph 12 .
  Appeals against the final decision may be submitted to the Administration Board of FCiências.ID ( [e-mail] ) within 15 business days after the notification date.

Note 1: The documents that prove the entitlement of the academic qualifications and diplomas can be dismissed during the application period and replaced by a declaration on their honour from the applicant ( Minuta PT , Minute EN ) . Their delivery is mandatory for the fellowship contractualization.

Number of offers available 1 Company/Institute BioISI - Biosystems and Integrative Sciences Institute Country Portugal State/Province Lisboa City Lisboa Postal Code 1749-016 Street Campus da Faculdade de Ciências da Universidade de Lisboa Geofield