Scientist I – Assay Development & Screening

Ryvu; Kraków; Hybrid; PLN 150,000 - 210,000; Full time

Benefits offered by this job

Luxmed

Multisport

PZU

Language Courses

Job summary

Ryvu Therapeutics in Kraków seeks a Scientist I to join the Assay Development & Screening group, supporting oncology discovery from HTS to dose-response profiling. The role emphasizes designing and executing plate-based biochemical and cell-based assays, with emphasis on automation and data analysis.

You will work under senior scientists, train associates, and help standardize SOPs, with opportunity for rapid scientific growth in a collaborative environment.

Qualifications

• MSc in biotechnology, biochemistry, molecular biology or related field with ≥3 years of experience, or a PhD with 0–1 year.
• Hands-on assay development and HTS experience in pharma/biotech/CRO.
• Experience with lab automation and data analysis.
• Ability to lead small work packages and present results clearly.
• Basic use of approved AI tools, in line with SOPs and data protection rules.
• English B2+

Responsibilities

• Plan and execute assay development, optimization and screening work packages.
• Develop and run plate-based biochemical and cell-based assays.
• Characterize compound–target binding and kinetics.
• Run HTS and dose–response campaigns with automated liquid handling.
• Design controls, analyze data (IC50/EC50, Z'), draw conclusions.
• Present results and train associate scientists.

Skills

Assay development

HTS experience

Lab automation

Data analysis

Project leadership

English (B2+)

Education

MSc in Biotechnology

PhD (0-1 year)

Tools

SPR

MST

HCS

Cell culture

Job description

Scientist I – Assay Development & Screening

We are looking for a Scientist I to join our Assay Development & Screening group, which builds and runs biochemical, biophysical and cell-based assays supporting Ryvu’s oncology discovery projects, from HTS to dose-response profiling.

KEY RESPONSIBILITIES

• Independently plan and execute assay development, optimization and screening work packages aligned with project goals
• Develop and run plate-based assays (TR-FRET/HTRF, AlphaLISA, fluorescence, luminescence, ELISA), both biochemical and cell-based
• Characterize compound–target binding and kinetics (e.g., SPR, MST)
• Run HTS and dose-response campaigns using automated liquid handling
• Design controls, analyze data (IC50/EC50, Z′), draw conclusions and propose next steps
• Author and standardize protocols and SOPs, and keep traceable records in ELN
• Present results, collaborate cross-functionally and with CROs, and train associate scientists

YOUR BACKGROUND

• MSc in biotechnology, biochemistry, molecular biology or a related field with ≥3 years of relevant experience, or a PhD with 0–1 year
• Hands‑on assay development and/or HTS experience in pharma, biotech or a CRO
• Experience with lab automation and data analysisAbility to lead small work packages and present results clearly
• Basic use of approved AI tools, in line with SOPs and data protection rules
• English B2+

Nice to have

• SPR, MST, HCS, cell culture

YOUR BENEFIT PACKAGE

• Work in one of the most innovative companies in the region with a proven track record and high perspective of growth
• Participation in challenging and ambitious projects and opportunity for rapid scientific and business career development
• Collaborative and supportive work culture
  
• Training and development opportunities enabling scientific development
• Package of benefits: Luxmed, Multisport, PZU
• Language Courses (English/Polish)