Scientist I – Assay Development & Screening

Ryvu Therapeutics; Kraków; On-site; PLN 60,000 - 90,000; Full time

Benefits offered by this job

Luxmed

Multisport

PZU

Language Courses (English/Polish)

Job summary

Ryvu Therapeutics is seeking a Scientist I to join the Assay Development & Screening group, contributing to biochemical, biophysical and cell-based assays supporting oncology discovery from HTS to dose-response profiling.

You will independently plan and execute assay development, run plate-based assays, characterize target binding with SPR/MST, and perform HTS campaigns, while preparing SOPs and training junior staff. English proficiency with SOP compliance is required.

Qualifications

• MSc in biotechnology, biochemistry, molecular biology or a related field with ≥3 years of relevant experience, or a PhD with 0-1 year
• Hands-on assay development and/or HTS experience in pharma, biotech or a CRO
• Experience with lab automation and data analysis
• Ability to lead small work packages and present results clearly
• Basic use of approved AI tools, in line with SOPs and data protection rules
• English B2+

Responsibilities

• Independently plan and execute assay development, optimization and screening work packages aligned with project goals
• Develop and run plate-based assays (TR-FRET/HTRF, AlphaLISA, fluorescence, luminescence, ELISA), both biochemical and cell-based
• Characterize compound target binding and kinetics (e.g., SPR, MST)
• Run HTS and dose-response campaigns using automated liquid handling
• Design controls, analyze data (IC50/EC50, Z′), draw conclusions and propose next steps
• Author and standardize protocols and SOPs, and keep traceable records in ELN
• Present results, collaborate cross-functionally and with CROs, and train associate scientists

Skills

Assay development

HTS experience

Lab automation

Data analysis

Team leadership

English (B2+)

Education

MSc in biotechnology/biochemistry/molecular biology or related field

PhD with 0-1 year experience (optional)

Tools

SPR

MST

Job description

We are looking for a Scientist I to join our Assay Development & Screening group, which builds and runs biochemical, biophysical and cell-based assays supporting Ryvu’s oncology discovery projects, from HTS to dose-response profiling.

Key Responsibilities

• Independently plan and execute assay development, optimization and screening work packages aligned with project goals
• Develop and run plate-based assays (TR-FRET/HTRF, AlphaLISA, fluorescence, luminescence, ELISA), both biochemical and cell-based
• Characterize compound target binding and kinetics (e.g., SPR, MST)
• Run HTS and dose-response campaigns using automated liquid handling
• Design controls, analyze data (IC50/EC50, Z′), draw conclusions and propose next steps
• Author and standardize protocols and SOPs, and keep traceable records in ELN
• Present results, collaborate cross-functionally and with CROs, and train associate scientists

YOUR BACKGROUND

• MSc in biotechnology, biochemistry, molecular biology or a related field with ≥3 years of relevant experience, or a PhD with 0-1 year
• Hands-on assay development and/or HTS experience in pharma, biotech or a CRO
• Experience with lab automation and data analysis
• Ability to lead small work packages and present results clearly
• Basic use of approved AI tools, in line with SOPs and data protection rules
• English B2+

Nice to have

• SPR, MST, HCS, cell culture

YOUR BENEFIT PACKAGE

• Work in one of the most innovative companies in the region with a proven track record and high perspective of growth
• Participation in challenging and ambitious projects and opportunity for rapid scientific and business career development
• Collaborative and supportive work culture
• Training and development opportunities enabling scientific development
• Package of benefits: Luxmed, Multisport, PZU
• Language Courses (English/Polish)