Scientist I/II - Biology

Ryvu Therapeutics; Kraków; On-site; PLN 60,000 - 110,000; Full time

Benefits offered by this job

Luxmed

Multisport

Relocation assistance

Job summary

Ryvu Therapeutics in Kraków seeks a Biologist/Biotechnologist to establish and characterize patient-derived cellular models. You will balance hands-on laboratory work with conceptual scientific development and own assigned tasks.

Responsibilities include 2D/3D cell-based assays, mammalian cell culture, and techniques like ELISA, Western blot, qPCR, and flow cytometry. Strong English and independent work skills are essential for success.

Qualifications

• MSc in Molecular Biology, Biotechnology, or related field with 2+ years of experience, or PhD.
• Cancer biology experience is highly desirable.
• Proven experience in developing 2D and 3D cell-based assays.
• Hands-on mammalian cell culture including patient-derived/organoid models is a plus; standard molecular biology techniques include ELISA, Western blot, qPCR, and flow cytometry.
• Experience with medium-throughput cell-based assays in microplate formats.

Responsibilities

• Establishment and maintenance of primary cell cultures.
• Design and execution of complex experiments (e.g., CRISPR screens, target validation, pharmacology assays).
• Biological data interpretation and scientific conclusion drawing.
• Development and implementation of new research methods and protocols.
• Regular presentation of results in internal meetings and project reviews.

Skills

Team collaboration

Independent work

Analytical thinking

English communication

Education

MSc in Molecular Biology

PhD in related field

Tools

FlowJo

GraphPad Prism

Excel

Job description

We are looking for a team-oriented and independent Biologist or Biotechnologist with a strong background in the establishment and characterization of patient-derived cellular models and solid technical expertise (e.g., RNAi/CRISPR, flow cytometry, Western blot, qPCR) to support and enhance our discovery and development process. This position offers a unique opportunity to combine hands-on laboratory work with conceptual scientific development, with full ownership of assigned tasks.

Key Responsibilities

• Laboratory-based role: approximately 70% wet lab work, 30% data analysis and conceptual input
• Establishment and maintenance of primary cell cultures
• Design and execution of complex and technically challenging experiments, including:
• Whole-genome CRISPR screens for target identification
• Target validation studies
• Secondary functional assays in pharmacology
• Biological data interpretation and drawing relevant scientific conclusions
• Development and implementation of new research methods and protocols based on project needs
• Continuous literature review and integration of findings into project strategies
• Independent management of dedicated sub-projects
• Regular presentation of research results and methodologies in internal meetings and project reviews

YOUR BACKGROUND

• MSc in Molecular Biology, Biotechnology, or related field with at least 2 years of experience in academia or industry, or a PhD degree
• Previous experience in cancer biology is highly desirable
• Proven experience in developing 2D and 3D cell-based assays
• Hands-on expertise in mammalian cell culture, with experience in patient-derived and/or organoid models considered a plus, and common molecular biology techniques:
• ELISA, Western blot, qPCR, flow cytometry
• Cytotoxicity and proliferation assays
• Evaluation of drug synergy
• Experience with medium-throughput cell-based assays in microplate format
• Proficiency in data analysis software such as GraphPad Prism, Excel, FlowJo
• Experience with primary cell cultures, biologics activity testing, and gene silencing/knock-out techniques (RNAi and/or CRISPR) is a plus
• Strong analytical thinking, literature research skills, and ability to work independently
• Eagerness to learn and apply new experimental methods
• Good command of written and spoken English

YOUR BENEFIT PACKAGE

• Work in one of the most innovative companies in the region with a proven track record and high perspective of growth
• Collaborative and supportive work culture
• Training program enabling scientific development: Ryvu Academy, scientific lectures, participation in conferences
• Package of benefits: Luxmed, Multisport
• Onsite support for foreigners and help with relocation