Postdoctoral Fellow — 3D Tissue Models & Secretomics

Arbeidsplassen; Oslo; On-site; NOK 595,000 - 690,000; Full time

Job summary

University of Oslo is inviting applications for a Postdoctoral Fellow to develop advanced 3D in vitro models for understanding oral biology, disease mechanisms, tissue regeneration and biomaterial–cell interactions. The successful candidate will work with spheroids, organoids, and tissue-engineered constructs, exploring secretomics, exosome analyses, and imaging to reveal cellular responses.

The role supports publishing, grant writing, and interdisciplinary collaboration.

Qualifications

• PhD in Cell Biology, Molecular Biology, Biotechnology, Biomedical Sciences, Tissue Engineering, Regenerative Medicine, Biomaterials, or a closely related field.
• Documented experience with mammalian cell culture and 3D in vitro models; position the Celvivo system or similar rotational system.
• Experience with secretome/secretomics, extracellular vesicles/exosomes, proteomics, or related molecular approaches.
• Documented experience in optimizing, validating, and executing high-multiplex protein panels for cytokine and biomarker quantification across various biological matrices (e.g., serum, plasma, cell culture supernatants).
• Experience with microscopy and cellular or molecular characterization.
• Good oral and written communication skills in English.

Responsibilities

• Develop, optimize and validate advanced 3D cell culture models, including spheroids, organoids and tissue-engineered constructs.
• Establish and apply rotational 3D culture systems such as CelVivo or comparable platforms.
• Design and perform experiments investigating cell-cell and biomaterial-cell interactions.
• Perform secretome and extracellular vesicle/exosome analyses.
• Optimize and apply high-multiplex protein assays for cytokine and biomarker profiling in biological samples and cell-culture supernatants.
• Perform microscopy and cellular and molecular characterization, including advanced imaging where appropriate.
• Integrate and interpret imaging, molecular and omics-derived datasets.
• Contribute to the analysis of clinical samples and biopsies where relevant.
• Participate in scientific writing, dissemination and preparation of publications and research proposals.
• Contribute actively to the collaborative research environment of BIOMAT and associated research groups.

Skills

3D cell culture

Mammalian cell culture

Secretomics

Microscopy

English communication

Education

PhD in Cell Biology

Tools

CelVivo system

Proteomics workflows

Job description

University of Oslo is inviting applications for a Postdoctoral Fellow to develop advanced 3D in vitro models for understanding oral biology, disease mechanisms, tissue regeneration and biomaterial–cell interactions. The successful candidate will work with spheroids, organoids, and tissue-engineered constructs, exploring secretomics, exosome analyses, and imaging to reveal cellular responses.

The role supports publishing, grant writing, and interdisciplinary collaboration.