Manufacturing Operator (Shift Based)

SIRE LIFE SCIENCES; Breda; On-site; EUR 32,000 - 45,000; Full time

Job summary

SIRE Life Sciences currently seeks a Manufacturing Operator (GMP) to join a dynamic production team in the Netherlands. You will oversee automated lines, ensuring safe, compliant operation and supporting improvement through troubleshooting and process optimisation.

Key duties include equipment setup, changeovers, data entry in SAP/MES, and collaboration with Quality, Maintenance and Production teams. A GMP background and English communication are required. Shift rotations apply.

Qualifications

• Technical education at MBO level or an equivalent qualification such as VAPRO B.
• Experience in automated production, packaging, or process manufacturing.
• Experience in GMP or other regulated manufacturing environments is desirable.
• Knowledge of SAP, MES or comparable production software.

Responsibilities

• Operate automated production and packaging equipment per GMP requirements and SOPs.
• Prepare lines for operation with setups, changeovers, cleaning, and line clearance.
• Investigate and resolve equipment faults to minimise downtime.
• Fine‑tune machine settings to improve productivity and quality.
• Record production data using SAP, MES, and related systems.
• Complete batch records and equipment logs accurately.
• Assist with deviation investigations and root cause analysis.
• Collaborate with Production, Maintenance and Quality to restore performance.
• Drive continuous improvement with Lean principles to optimise processes.
• Promote safety and clear communication during shift handovers.

Skills

Troubleshooting

English communication

Lean/Kaizen

Problem solving

Education

MBO level / VAPRO B

Tools

SAP

MES

Job description

Company

Our client is an international manufacturing company known for operating within a highly regulated production environment. Using advanced automated manufacturing and packaging technologies, the organisation is committed to delivering high-quality products while maintaining the highest standards of safety, compliance, and operational excellence. Continuous improvement, teamwork, and innovation are key drivers of success across the site.

Job Description

We are currently seeking an Manufacturing Operator(GMP) to join a dynamic production team. In this position, you will be responsible for ensuring automated production lines operate efficiently, safely, and in accordance with GMP guidelines. You will play an important role in maintaining equipment performance, resolving technical issues, and supporting production continuity through proactive problem-solving and process optimisation.

Key Responsibilities

• Work with automated production and packaging equipment in accordance with GMP requirements and standard operating procedures.
• Prepare production lines for operation by carrying out equipment set-ups, product changeovers, cleaning activities, and line clearance procedures.
• Investigate and resolve equipment faults and process disruptions to minimise production downtime.
• Fine-tune machine settings and process parameters to improve productivity, efficiency, and product quality.
• Register and verify production information using SAP, MES, and related manufacturing systems.
• Complete production documentation accurately, including batch records, equipment logs, and operational documentation.
• Assist with deviation investigations and support root cause analysis using structured troubleshooting methodologies.
• Collaborate with Production, Maintenance, and Quality teams to resolve technical issues and restore production performance.
• Drive continuous improvement initiatives by applying Lean principles and identifying opportunities to optimise manufacturing processes.
• Promote a safe working environment while ensuring effective communication during shift handovers.

Requirement

• Technical education at MBO level or an equivalent qualification such as VAPRO B.
• Previous experience within automated production, assembly, packaging, or process manufacturing.
• Strong technical aptitude with proven troubleshooting and analytical problem-solving skills.
• Familiarity with structured improvement methodologies including Root Cause Analysis (RCA), 5 Why, Lean, or Kaizen.
• Experience working within GMP or another regulated manufacturing environment is highly desirable.
• Knowledge of SAP, Manufacturing Execution Systems (MES), or comparable production software.
• Good communication skills in English.
• Flexible to work rotating 3-shift and 5-shift schedules.
• Available for a temporary full-time assignment via SIRE Life Sciences.

Why Apply?

This opportunity is ideal for someone who enjoys working with advanced manufacturing technology and takes pride in improving production performance. You'll become part of an environment where technical expertise, teamwork, and continuous improvement are valued every day. If you're looking for your next challenge in automated manufacturing, we'd love to hear from you.