Lead Process Engineer – CAR-T Cell Therapy Manufacturing

Bristol Myers Squibb EU Policy; Leiden; On-site; EUR 120,000 - 190,000; Full time

Job summary

Bristol Myers Squibb Netherlands is seeking a Manager of Process Engineering to lead the technical direction for CAR‑T cell therapy production at the Leiden facility, supporting 24/7 operations for clinical and commercial supply.

The role collaborates with Process Validation, MES/Automation, Manufacturing, and Quality to deliver compliant, cost‑effective products while driving continuous improvement and regulatory readiness.

Qualifications

• Bachelor's degree in relevant science or engineering; advanced degree preferred.
• Minimum 8 years in cGMP biologics manufacturing, preferably in cell therapy.
• Lean Manufacturing principles knowledge required.
• Experience leading cross‑functional teams and external parties.
• Strong communication and leadership skills.

Responsibilities

• Drive end-to-end process optimization for 24/7 Leiden operations.
• Provide technical guidance for process investigations and deviations.
• Ensure timely review/approval of process documentation and change controls.
• Lead cross-functional collaboration with Manufacturing, Quality, and Supply Chain.
• Support regulatory inspections and preparation of inspection readiness.
• Oversee development and deployment of new technology and systems for production.

Skills

Facility design

Cell therapy

Automation/SCADA

People management

Regulatory compliance

Lean manufacturing

Education

Bachelors in science/engineering

Advanced degree preferred

Job description

Bristol Myers Squibb Netherlands is seeking a Manager of Process Engineering to lead the technical direction for CAR‑T cell therapy production at the Leiden facility, supporting 24/7 operations for clinical and commercial supply.

The role collaborates with Process Validation, MES/Automation, Manufacturing, and Quality to deliver compliant, cost‑effective products while driving continuous improvement and regulatory readiness.