Executive/Sr Executive - R&D (Process Development) Research & Development · Ambernath

PolyPeptide; Ambernath; On-site; INR 800,000 - 1,200,000; Full time

Job summary

PolyPeptide Group in Ambernath, India, is hiring for Executive/Sr Executive - Process Development. The role requires a strong foundation in organic chemistry, peptide chemistry, and process development, with independent project execution and DSP/SPPS experience.

You will drive purification strategies, optimize reactions, and ensure safety and regulatory compliance. The candidate should have hands-on SPPS experience, proficiency in chromatography, and a meticulous approach to documentation,

Qualifications

• Ph.D. in Chemistry with 1–3 years of relevant experience.
• M.Sc in Organic Chemistry or equivalent with >5 years of relevant experience.

Responsibilities

• Independently manage projects, designing purification/ROS strategies and conducting R&D scale experiments.
• Perform peptide API purification using chromatographic techniques.
• Plan and execute DSP activities with reproducible results.
• Operate, clean, and maintain instruments per SOPs.
• Maintain accurate documentation and process logs.
• Collaborate across departments for seamless coordination.

Skills

SPPS

Peptide Chemistry

Chromatography

Independent Project Management

Documentation & Recordkeeping

Education

Ph.D. in Chemistry

M.Sc in Organic Chemistry

Tools

Preparative HPLC

SPPS hardware

Job description

Location: Ambernath, India

Job Type: Full Time

Reporting: Sr. Manager - Research & Development

About PolyPeptide Group:

PolyPeptide Group AG and its consolidated subsidiaries ("PolyPeptide") is a specialized

Contract Development & Manufacturing Organization (CDMO) for peptide- and

oligonucleotide-based active pharmaceutical ingredients. By supporting its customers

mainly in pharma and biotech, it contributes to the health of millions of patients across the

world. PolyPeptide serves a fast-growing market, offering products and services from pre

clinical to commercial stages. Its broad portfolio reflects the opportunities in drug

therapies across areas and with a large exposure to metabolic diseases, including GLP-1.

Dating back to 1952, PolyPeptide today runs a global network of six GMP-certified facilities

in Europe, the U.S. and India. PolyPeptide’s shares (SIX: PPGN) are listed on SIX Swiss

Exchange.

Position Overview:

We are looking for a highly skilled and motivated professional to join our team as Executive/Sr Executive - Process Development. The ideal candidate will possess a strong foundation in Organic Chemistry and proven expertise in peptide chemistry and process development. This role requires independent project execution, technical proficiency in DSP, and SPPS synthesis, and a collaborative approach to drive innovation and ensure process excellence. The successful candidate will demonstrate exceptional problem-solving abilities, meticulous attention to detail, and a commitment to safety and regulatory

compliance.

Key Responsibilities:

• Independently manage projects, including designing Purification Strategies, Reaction Optimization Strategies (ROS) and conducting R&D scale experiments
• Perform Peptide API purification using Chromatography techniques like Preparative HPLC, IEC
• Plan and execute DSP (Down Stream Purification) activities with reproducible Result
• Having Solid Phase Peptide Synthesis (SPPS) experience
• Operate, clean, and maintain instruments/equipment in accordance with SOPs
• Identify and recommend improvements for continuous process optimization
• Maintain accurate and timely documentation, including online records, process logs, and R&D documentation
• Collaborate effectively across departments to ensure seamless coordination
• Adhere to all safety protocols and utilize appropriate personal protective equipment (PPE)

Required Skills & Qualifications:

• Experience/Education:
• Ph.D. in Chemistry 1-3 yrs relevant experience; M.Sc in Organic/or equivalent, >5 yrs relevant experience

Key Skills & Competencies:

• Strong knowledge of peptide chemistry Column Chromatography
• Hands-on experience with SPPS
• Ability to work independently and manage multiple projects simultaneously
• Excellent documentation and organizational skills
• Strong communication and cross-functional collaboration abilities

Why Join Us at PolyPeptide Group:

PolyPeptide Group offers an exciting opportunity to work at the forefront of peptide-based

therapeutics, a rapidly growing and innovative segment of the pharmaceutical industry. As

a key member of PolyPeptide team, you will have the opportunity to contribute to a

company that is dedicated to the success of its clients and the advancement of peptide

science. Join us and be part of a global organization that is shaping the future of life-saving

therapies.