Executive/Sr Executive - R&D (Process Development)

PolyPeptide Group; Thane; On-site; INR 1,200,000 - 1,800,000; Full time

Job summary

PolyPeptide Group is seeking an Executive/Sr Executive – Process Development in Ambernath, India. The role requires a strong foundation in organic chemistry and extensive peptide chemistry/process development experience. You will lead projects, design purification strategies, and drive DSP/SPSS activities with a focus on quality and regulatory compliance.

The candidate should have a Ph.D. in Chemistry (or M.Sc.

Qualifications

• Ph.D. in Chemistry with 1-3 yrs relevant experience; M.Sc. in Organic/equivalent with >5 yrs relevant experience.
• Solid Phase Peptide Synthesis (SPSS) experience.
• Experience in DSP and SPSS synthesis with cleanroom/compliance awareness.

Responsibilities

• Independently manage projects, including purification strategies, ROS and R&D scale experiments.
• Perform peptide API purification using chromatography (Preparative HPLC, IEC).
• Plan and execute DSP activities with reproducible results.

Skills

Peptide chemistry

Column chromatography

SPSS

Independent work

Documentation

Communication

Cross-functional teamwork

Education

Ph.D. in Chemistry

M.Sc. in Organic Chemistry

Job description

Location: Ambernath, India

Job Type: Full Time

Reporting: Sr. Manager - Research & Development

About PolyPeptide Group

PolyPeptide Group AG and its consolidated subsidiaries (“PolyPeptide”) is a specialized Contract Development & Manufacturing Organization (CDMO) for peptide- and oligonucleotide-based active pharmaceutical ingredients. By supporting its customers mainly in pharma and biotech, it contributes to the health of millions of patients across the world. PolyPeptide serves a fast-growing market, offering products and services from preclinical to commercial stages. Its broad portfolio reflects the opportunities in drug therapies across areas and with a large exposure to metabolic diseases, including GLP-1. Dating back to 1958, PolyPeptide today runs a global network of six GMP-certified facilities in Europe, the U.S. and India. PolyPeptide’s shares (SIX: PPGN) are listed on SIX Swiss Exchange.

Position Overview

We are looking for a highly skilled and motivated professional to join our team as Executive/Sr Executive – Process Development. The ideal candidate will possess a strong foundation in Organic Chemistry and proven expertise in peptide chemistry and process development. This role requires independent project execution, technical proficiency in DSP, and SPSS synthesis, and a collaborative approach to drive innovation and ensure process excellence. The successful candidate will demonstrate exceptional problem-solving abilities, meticulous attention to detail, and a commitment to safety and regulatory compliance.

Key Responsibilities

• Independently manage projects, including designing Purification Strategies, Reaction Optimization Strategies (ROS) and conducting R&D scale experiments
• Perform Peptide API purification using Chromatography techniques like Preparative HPLC, IEC
• Plan and execute DSP (Down Stream Purification) activities with reproducible

Result

• Having Solid Phase Peptide Synthesis (SPSS) experience
• Operate, clean, and maintain instruments/equipment in accordance with SOPs
• Identify and recommend improvements for continuous process optimization
• Maintain accurate and timely documentation, including online records, process logs, and R&D documentation
• Collaborate effectively across departments to ensure seamless coordination
• Adhere to all safety protocols and utilize appropriate personal protective equipment

Required Skills & Qualifications

Ph.D. in Chemistry 1-3 yrs relevant experience; M.Sc. in Organic/or equivalent, >5 yrs relevant experience

Key Skills & Competencies

• Strong knowledge of peptide chemistry Column Chromatography
• Hands-on experience with SPSS
• Ability to work independently and manage multiple projects simultaneously
• Excellent documentation and organizational skills
• Strong communication and cross-functional collaboration abilities

Why Join Us at PolyPeptide Group

PolyPeptide Group offers an exciting opportunity to work at the forefront of peptide-based therapeutics, a rapidly growing and innovative segment of the pharmaceutical industry. As a key member of PolyPeptide team, you will have the opportunity to contribute to a company that is dedicated to the success of its clients and the advancement of peptide science. Join us and be part of a global organization that is shaping the future of life-saving therapies.