Postdoc: Nose-to-Brain Hydrogel Peptide Delivery

Times Higher Education; Hong Kong; On-site; HKD 420,000 - 540,000; Full time

Benefits offered by this job

Annual leave

Medical benefits

On-campus gyms and libraries

Job summary

The University of Hong Kong invites applications for a Post-doctoral Fellow in Hydrogel-Enabled Peptide Brain Delivery. Join the JC STEM Lab of Nanomedicine for Advanced Therapy to develop a nose-to-brain hydrogel platform targeting ND diseases.

Lead synthesis, characterization, and evaluation of peptide analogues and hydrogels designed to bypass the BBB. The role covers peptide chemistry, nanomaterial engineering, in vitro and in vivo studies, and translational modelling, with emphasis on

Qualifications

• Ph.D. in Pharmaceutical Sciences, Chemistry, Biochemistry, Bioengineering, Molecular Biology, or a related field.
• Strong biological skills with a proven track record of high-quality research involving peptide or nanomaterial-based therapeutics.
• Demonstrated experience in scientific writing and publication.

Responsibilities

• Plan and conduct peptide and hydrogel syntheses and bioconjugation work.
• Operate analytical tools such as HPLC, LC-MS, 1H-NMR, GPC and SPR.
• Design, cross-link, and characterize polymer-based nanomaterials and hydrogels.
• Perform ELISA, Western blotting, immunohistochemistry, and cell culture assays.
• Carry out in vivo rodent studies including PK sampling and behavioural testing.
• Collaborate with team mates on model development and data sharing.
• Prepare study protocols, reports, and contribute to manuscripts.
• Supervise undergraduate and postgraduate students and disseminate findings.

Skills

Peptide synthesis

Hydrogel synthesis

Bioconjugation chemistry

Analytical instrumentation

ELISA

Western blotting

Immunohistochemistry

Cell culture

In vivo rodent models

Pharmacokinetic sampling

Behavioural testing

Grant/writing contributions

Education

Ph.D. in Pharmaceutical Sciences, Chemistry, Biochemistry, Bioengineering, Molecular Biology, or a related field

Tools

HPLC

LC-MS

NMR

GPC

Radiolabelling

Design-Expert

Job description

The University of Hong Kong invites applications for a Post-doctoral Fellow in Hydrogel-Enabled Peptide Brain Delivery. Join the JC STEM Lab of Nanomedicine for Advanced Therapy to develop a nose-to-brain hydrogel platform targeting ND diseases.

Lead synthesis, characterization, and evaluation of peptide analogues and hydrogels designed to bypass the BBB. The role covers peptide chemistry, nanomaterial engineering, in vitro and in vivo studies, and translational modelling, with emphasis on