Senior Scientist, Synthetic Genomics — Lab-Driven Genomics

One Nucleus; Cambridge; On-site; GBP 45,000 - 70,000; Full time

Benefits offered by this job

Discretionary annual performance bonus

Company pension (matching up to 8%)

Life assurance

Private medical insurance

Group income protection

Employee long term incentive scheme

On-site parking

Dog friendly office

Job summary

Constructive Bio in Cambridge is seeking a Scientist or Senior Scientist in Synthetic Genomics to design and execute genome synthesis strategies, focusing on reprogrammed genetic codes for protein production.

You will contribute to the platform by robust experimental design, thorough documentation, and collaboration with engineers, bioinformaticians and scientists to advance our Genomics programs and industrial-scale workflows.

Qualifications

• PhD or equivalent in molecular biology, microbiology, biochemistry or bioengineering.
• Experience designing and executing DNA cloning strategies.
• Engineering mindset with ability to design, build and troubleshoot genetic systems.
• Experience interpreting sequencing data (Illumina / Oxford Nanopore).
• Proficient in prokaryotic DNA manipulation techniques.

Responsibilities

• Design and execute experimental strategies for genome synthesis and large DNA assembly.
• Develop synthetic microorganisms with reprogrammed genetic codes for production.
• Document experiments thoroughly and communicate progress to teams.
• Collaborate with experimental and computational colleagues to deliver results.

Skills

DNA cloning design

Problem solving

Independent work

Communication skills

Team collaboration

Education

PhD or equivalent in molecular biology

Tools

Gibson Assembly

Golden Gate Assembly

DNA sequencing tools

Illumina

Oxford Nanopore

Job description

Constructive Bio in Cambridge is seeking a Scientist or Senior Scientist in Synthetic Genomics to design and execute genome synthesis strategies, focusing on reprogrammed genetic codes for protein production.

You will contribute to the platform by robust experimental design, thorough documentation, and collaboration with engineers, bioinformaticians and scientists to advance our Genomics programs and industrial-scale workflows.